CAS RN: 1160169-39-0
rac 5-Keto Fluvastatin
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20260514 | 1mg | Out of stock | 30 business days | Inquiry |
- Product code: starshine_CAS1160169-39-0
- Purity/Analytical Methods: >99.0%
1160169-39-0 / (E)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3-hydroxy-5-oxohept-6-enoic acid
rac 5-Keto Fluvastatin | (Rac)-5-Keto Fluvastatin | Fluvastatin EP Impurity D
Basic Information
CAS
1160169-39-0
Multi CAS
Yes
Molecular Formula
C24H24FNO4
Molecular Weight
409.400000
Exact Mass
409.168936
SMILES
CC(C)N1C2=CC=CC=C2C(=C1/C=C/C(=O)CC(CC(=O)O)O)C3=CC=C(C=C3)F
InChI
InChI=1S/C24H24FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,19,28H,13-14H2,1-2H3,(H,29,30)/b12-11+
InChIKey
FSIBOMHNSMFWBF-VAWYXSNFSA-N
Synonyms
rac 5-Keto Fluvastatin
(Rac)-5-Keto Fluvastatin
Fluvastatin EP Impurity D
UNII-8LLT21950O
8LLT21950O
Computed Properties
Structural Parameters
Heavy atom count
30
Aromatic heavy atom count
15
Fraction Csp3
0.25
Rotatable bonds
8
H-bond acceptors
4
H-bond donors
2
Molar refractivity
114.63
TPSA
79.53
LogP / Solubility
WLOGP
4.84
MLOGP
4.28
XLogP3
3.4
Consensus LogP
4.17
Log S (ESOL)
-5.27
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.41
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.3
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.78
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
3
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