CAS RN: 112529-15-4
Pioglitazone Hydrochloride
Product Availability
Choose a grade to view its available package options.
9 package records9 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250703 | 100g | In stock | Shanghai, Chengdu | Inquiry |
| Batchno.20260409 | 10g | In stock | Shanghai, Tianjin, Wuhan, Chengdu | Inquiry |
| Batchno.20250411 | 1g | In stock | Shanghai, Shenzhen, Tianjin | Inquiry |
| Batchno.20260228 | 1mg | In stock | Shanghai, Tianjin, Wuhan | Inquiry |
| Batchno.20250914 | 250mg | In stock | Shanghai | Inquiry |
| Batchno.20251030 | 25g | In stock | Shanghai, Tianjin | Inquiry |
| Batchno.20250926 | 25mg | In stock | Shanghai, Tianjin | Inquiry |
| Batchno.20250818 | 500g | In stock | Shanghai | Inquiry |
| Batchno.20260309 | 5g | In stock | Shanghai, Tianjin | Inquiry |
- Product code: ICTP1901
- Purity/Analytical Methods: >98.0%(HPLC)(N)
112529-15-4 / 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydrochloride
pioglitazone hydrochloride | Pioglitazone HCl | Piomed
Basic Information
CAS
112529-15-4
Multi CAS
Yes
Molecular Formula
C19H21ClN2O3S
Molecular Weight
392.900000
Exact Mass
392.096141
SMILES
CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3.Cl
InChI
InChI=1S/C19H20N2O3S.ClH/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17;/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23);1H
InChIKey
GHUUBYQTCDQWRA-UHFFFAOYSA-N
Synonyms
pioglitazone hydrochloride
Pioglitazone HCl
Piomed
JQT35NPK6C
Pioglitazone (as hydrochloride)
Computed Properties
Structural Parameters
Heavy atom count
26
Aromatic heavy atom count
12
Fraction Csp3
0.32
Rotatable bonds
7
H-bond acceptors
5
H-bond donors
1
Molar refractivity
105.13
TPSA
68.29
LogP / Solubility
WLOGP
3.58
MLOGP
3.17
XLogP3
3.58
Consensus LogP
3.44
Log S (ESOL)
-4.41
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.37
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-6.03
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.57
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
3
Safety & Transport
Pictogram(s)
Irritant
Health Hazard
Signal
Warning
GHS Hazard Statements
H302 (12.3%): Harmful if swallowed [Warning Acute toxicity, oral]
H319 (80.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H361 (10.5%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
Precautionary Statement Codes
P203, P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P318, P330, P337+P317, P405, and P501
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- CAS RN: 105816-04-4
- Product Code: ICTN0912
- Purity/Analytical method: >98.0%(T)(HPLC)
