CAS RN: 1109276-89-2
PF-04620110
Product Availability
Choose a grade to view its available package options.
7 package records5 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250803 | 100mg | In stock | Shanghai | Inquiry |
| Batchno.20250606 | 10mg | Out of stock | Inquiry | |
| Batchno.20251209 | 250mg | Out of stock | Inquiry | |
| Batchno.20260114 | 25mg | In stock | Shanghai | Inquiry |
| Batchno.20250528 | 50mg | In stock | Shanghai | Inquiry |
| Batchno.20251114 | 5mg | In stock | Shanghai | Inquiry |
| Batchno.20250716 | 5mg / 25mg | Confirm by inquiry | Shanghai | Inquiry |
- Product code: starshine_CAS1109276-89-2
- Purity/Analytical Methods: >99.0%
1109276-89-2 / 2-[4-[4-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]acetic acid
PF-04620110 | PF 04620110 | PF-4620110
Basic Information
CAS
1109276-89-2
Multi CAS
Yes
Molecular Formula
C21H24N4O4
Molecular Weight
396.400000
Exact Mass
396.179755
SMILES
C1CC(CCC1CC(=O)O)C2=CC=C(C=C2)N3CCOC4=NC=NC(=C4C3=O)N
InChI
InChI=1S/C21H24N4O4/c22-19-18-20(24-12-23-19)29-10-9-25(21(18)28)16-7-5-15(6-8-16)14-3-1-13(2-4-14)11-17(26)27/h5-8,12-14H,1-4,9-11H2,(H,26,27)(H2,22,23,24)
InChIKey
GEVVQZHMFVFGLN-UHFFFAOYSA-N
Synonyms
PF-04620110
PF 04620110
PF-4620110
CQ4M18RLJW
CHEMBL1835919
Computed Properties
Structural Parameters
Heavy atom count
29
Aromatic heavy atom count
12
Fraction Csp3
0.43
Rotatable bonds
4
H-bond acceptors
6
H-bond donors
2
Molar refractivity
107.01
TPSA
118.64
LogP / Solubility
WLOGP
2.85
MLOGP
2.53
XLogP3
3.3
Consensus LogP
2.89
Log S (ESOL)
-4.13
Class (ESOL)
Slightly soluble
Log S (Ali)
-4.87
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-5.08
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.12
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3
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