[email protected]
CAS 1103500-20-4 LY-2562175 molecular structure lightbox
CAS RN: 1103500-20-4

LY-2562175

Product Availability

Choose a grade to view its available package options.

13 package records9 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250719 10mg In stock Inquiry
Batchno.20250624 1mg In stock Inquiry
Batchno.20250308 1mg / 5mg Out of stock 5-7 business days Inquiry
Batchno.20251011 25mg In stock Inquiry
Batchno.20251009 50mg In stock Inquiry
Batchno.20250106 5mg In stock Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20260305 100mg Out of stock Inquiry
Batchno.20251109 10mg In stock Shanghai Inquiry
Batchno.20250705 1mg In stock Shanghai Inquiry
Batchno.20260213 250mg Out of stock Inquiry
Batchno.20250128 25mg In stock Shanghai Inquiry
Batchno.20260224 50mg Out of stock Inquiry
Batchno.20250320 5mg In stock Shanghai Inquiry
  • Product code: starshine_CAS1103500-20-4
  • Purity/Analytical Methods: >99.0%
GET A QUOTE

1103500-20-4 / 6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-carboxylic acid

6-(4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic acid | 6-(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic Acid | RefChem:188006

Standard CAS: 1103500-20-4 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
1103500-20-4
Multi CAS
No
Molecular Formula
C28H27Cl2N3O4
Molecular Weight
540.400000
Exact Mass
539.137862
SMILES
CN1C=C(C2=C1C=C(C=C2)N3CCC(CC3)OCC4=C(ON=C4C5=C(C=CC=C5Cl)Cl)C6CC6)C(=O)O
InChI
InChI=1S/C28H27Cl2N3O4/c1-32-14-20(28(34)35)19-8-7-17(13-24(19)32)33-11-9-18(10-12-33)36-15-21-26(31-37-27(21)16-5-6-16)25-22(29)3-2-4-23(25)30/h2-4,7-8,13-14,16,18H,5-6,9-12,15H2,1H3,(H,34,35)
InChIKey
RPVDFHPBGBMWID-UHFFFAOYSA-N
Synonyms
6-(4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic acid 6-(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic Acid RefChem:188006 LY2562175 LY-2562175

Computed Properties

Structural Parameters

Heavy atom count
37
Aromatic heavy atom count
20
Fraction Csp3
0.36
Rotatable bonds
7
H-bond acceptors
6
H-bond donors
1
Molar refractivity
143.84
TPSA
80.73

LogP / Solubility

WLOGP
6.9
MLOGP
6.11
XLogP3
5.5
Consensus LogP
6.17
Log S (ESOL)
-7.48
Class (ESOL)
Insoluble
Log S (Ali)
-8.97
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-9.74
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.12

Drug-likeness / Medicinal Chemistry

Lipinski
No
Ghose
No
Veber
Yes
Egan
No
Muegge
No
Bioavailability score
0.17
Leadlikeness
No
Synthetic Accessibility
5.5

Customers Also Viewed

Get In Touch

Contact Us