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CAS 1100598-32-0 Tepotinib molecular structure lightbox
CAS RN: 1100598-32-0

Tepotinib

Product Availability

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12 package records12 with current stock3 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260531 100mg In stock Shanghai Inquiry
Batchno.20260514 1g In stock Shanghai, Tianjin Inquiry
Batchno.20250905 250mg In stock Shanghai Inquiry
Batchno.20250521 50mg In stock Shanghai, Shenzhen Inquiry
Batchno.20250313 5g In stock Shanghai Inquiry
Batchno.20250502 5mg In stock Shanghai Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260626 100mg In stock Inquiry
Batchno.20250521 10mg In stock Inquiry
Batchno.20250412 25mg In stock Inquiry
Batchno.20250307 50mg In stock Inquiry
Batchno.20250724 5mg In stock Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250504 1ml In stock Inquiry
  • Product code: SSC-011310
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 1g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1100598-32-0
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g ≥95% 0 Out of Stock Shanghai Inquiry

1100598-32-0 / 3-[1-[[3-[5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl]phenyl]methyl]-6-oxopyridazin-3-yl]benzonitrile

Tepotinib | EMD-1214063 | EMD 1214063

Standard CAS: 1100598-32-0 Multi CAS: No
Basic Information Computed Properties Safety & Transport

Basic Information

CAS
1100598-32-0
Multi CAS
No
Molecular Formula
C29H28N6O2
Molecular Weight
492.600000
Exact Mass
492.227374
SMILES
CN1CCC(CC1)COC2=CN=C(N=C2)C3=CC=CC(=C3)CN4C(=O)C=CC(=N4)C5=CC=CC(=C5)C#N
InChI
InChI=1S/C29H28N6O2/c1-34-12-10-21(11-13-34)20-37-26-17-31-29(32-18-26)25-7-3-5-23(15-25)19-35-28(36)9-8-27(33-35)24-6-2-4-22(14-24)16-30/h2-9,14-15,17-18,21H,10-13,19-20H2,1H3
InChIKey
AHYMHWXQRWRBKT-UHFFFAOYSA-N
Synonyms
Tepotinib EMD-1214063 EMD 1214063 EMD1214063 MSC-2156119J

Computed Properties

Structural Parameters

Heavy atom count
37
Aromatic heavy atom count
24
Fraction Csp3
0.28
Rotatable bonds
7
H-bond acceptors
8
Molar refractivity
140.93
TPSA
96.93

LogP / Solubility

WLOGP
4.01
MLOGP
3.56
XLogP3
3.4
Consensus LogP
3.66
Log S (ESOL)
-5.44
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.49
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.03
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.88

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
5

Safety & Transport

GHS Hazard Statements
Not Classified Reported as not meeting GHS hazard criteria by 1 of 1 companies. For more detailed information, please visit ECHA C&L website.

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