CAS RN: 1062368-62-0
LDN-193189 HCl
Product Availability
Choose a grade to view its available package options.
7 package records7 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260201 | 10mg | In stock | Shanghai | Inquiry |
| Batchno.20251213 | 1mg | In stock | Shanghai | Inquiry |
| Batchno.20250709 | 25mg | In stock | Shanghai | Inquiry |
| Batchno.20250610 | 2mg | In stock | Shanghai | Inquiry |
| Batchno.20260213 | 50mg | In stock | Shanghai, Wuhan | Inquiry |
| Batchno.20250801 | 5mg | In stock | Shanghai | Inquiry |
| Batchno.20260119 | 5mg / 25mg / 50mg / 250mg | Confirm by inquiry | Shanghai | Inquiry |
- Product code: starshine_CAS1062368-62-0
- Purity/Analytical Methods: >99.0%
1062368-62-0 / 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;hydrochloride
LDN-193189 monohydrochloride | PLH51K438W | Quinoline, 4-(6-(4-(1-piperazinyl)phenyl)pyrazolo(1,5-a)pyrimidin-3-yl)-, hydrochloride (1:1)
Basic Information
CAS
1062368-62-0
Multi CAS
Yes
Molecular Formula
C25H23ClN6
Molecular Weight
442.900000
Exact Mass
442.167273
SMILES
C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3.Cl
InChI
InChI=1S/C25H22N6.ClH/c1-2-4-24-22(3-1)21(9-10-27-24)23-16-29-31-17-19(15-28-25(23)31)18-5-7-20(8-6-18)30-13-11-26-12-14-30;/h1-10,15-17,26H,11-14H2;1H
InChIKey
PCCDKTWDGDFRME-UHFFFAOYSA-N
Synonyms
LDN-193189 monohydrochloride
PLH51K438W
Quinoline, 4-(6-(4-(1-piperazinyl)phenyl)pyrazolo(1,5-a)pyrimidin-3-yl)-, hydrochloride (1:1)
RefChem:1088385
LDN193189 Hydrochloride
Computed Properties
Structural Parameters
Heavy atom count
32
Aromatic heavy atom count
25
Fraction Csp3
0.16
Rotatable bonds
3
H-bond acceptors
6
H-bond donors
1
Molar refractivity
131.49
TPSA
58.35
LogP / Solubility
WLOGP
4.44
MLOGP
3.94
XLogP3
4.44
Consensus LogP
4.27
Log S (ESOL)
-5.77
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.4
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-6.59
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.27
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
4
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