CAS 1022150-12-4 Btk inhibitor 1 R enantiomer molecular structure

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CAS RN: 1022150-12-4

Btk inhibitor 1 R enantiomer

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4 package records4 with current stock1 grade group

Grade In stock only

Batch No.	Package	Availability	Inquiry
Batchno.20250303	1g	In stock	Inquiry
Batchno.20250823	250mg	In stock	Inquiry
Batchno.20250630	25g	In stock	Inquiry
Batchno.20250602	5g	In stock	Inquiry

Product code: SSC-003504

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Verified Factory Data

Supply Overview & Packaging Options

Packaging options, recorded purity, stock quantity and ship-from location below are generated from the current factory data table for this CAS.

Pack sizes on record: 1g, 0.25g, 5g, 10g, 25g, 100g
Available purity: >97%
Inventory rows with stock: 1
Bulk packaging: confirmed by inquiry

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Available Pack Sizes & Stock

Specific stock quantities are shown below. Price is not displayed online and is confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1022150-12-4
Pack Size	Recorded Purity	Available Qty	Ship From	Inquiry
1g	>97%	2 In Stock	Shanghai	Inquiry
0.25g	>97%	0 Out of Stock	Hong Kong	Inquiry
5g	>97%	0 Out of Stock	Shenzhen	Inquiry
10g	>97%	0 Out of Stock	Hong Kong	Inquiry
25g	>97%	0 Out of Stock	Shanghai	Inquiry
100g	>97%	0 Out of Stock	Shenzhen	Inquiry

1022150-12-4 / 3-(4-phenoxyphenyl)-1-[(3R)-piperidin-3-yl]pyrazolo[3,4-d]pyrimidin-4-amine

(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Ibrutinib N-desacryloyl impurity | NR6GN4MC2R

Standard CAS: 1022150-12-4 Multi CAS: Yes

Basic Information Computed Properties Safety & Transport

Basic Information

CAS

1022150-12-4

Multi CAS

Yes

Molecular Formula

C22H22N6O

Molecular Weight

386.400000

Exact Mass

386.185509

SMILES

C1C[C@H](CNC1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N

InChI

InChI=1S/C22H22N6O/c23-21-19-20(15-8-10-18(11-9-15)29-17-6-2-1-3-7-17)27-28(22(19)26-14-25-21)16-5-4-12-24-13-16/h1-3,6-11,14,16,24H,4-5,12-13H2,(H2,23,25,26)/t16-/m1/s1

InChIKey

GPSQYTDPBDNDGI-MRXNPFEDSA-N

Synonyms

(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Ibrutinib N-desacryloyl impurity NR6GN4MC2R 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-phenoxyphenyl)-1-(3R)-3-piperidinyl- (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine

Computed Properties

Structural Parameters

Heavy atom count

Aromatic heavy atom count

Fraction Csp3

0.23

Rotatable bonds

H-bond acceptors

H-bond donors

Molar refractivity

112.83

TPSA

90.88

LogP / Solubility

WLOGP

3.79

MLOGP

3.36

XLogP3

3.1

Consensus LogP

3.42

Log S (ESOL)

-4.9

Class (ESOL)

Slightly soluble

Log S (Ali)

-5.47

Class (Ali)

Slightly soluble

Log S (SILICOS-IT)

-5.8

Class (SILICOS-IT)

Slightly soluble

ADME

GI absorption

High

BBB permeant

P-gp substrate

CYP1A2 inhibitor

Yes

CYP2C19 inhibitor

Yes

CYP2C9 inhibitor

CYP2D6 inhibitor

Yes

CYP3A4 inhibitor

Yes

Log Kp (skin permeation)

-2.38

Drug-likeness / Medicinal Chemistry

Lipinski

Yes

Ghose

Yes

Veber

Yes

Egan

Yes

Muegge

Yes

Bioavailability score

0.55

Leadlikeness

Synthetic Accessibility

Safety & Transport

Pictogram(s)

Irritant Environmental Hazard

Signal

Warning

GHS Hazard Statements

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] H400 (50%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

Precautionary Statement Codes

P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501

Applications of CAS 1022150-12-4

This compound is commonly used in pharmaceutical research and drug discovery, general chemistry research and laboratory applications. Starshine Chemical supplies CAS 1022150-12-4 for R&D and pilot-scale use, with flexible pack sizes and purity grades available.

Physical & Chemical Properties

IUPAC Name

3-(4-phenoxyphenyl)-1-[(3R)-piperidin-3-yl]pyrazolo[3,4-d]pyrimidin-4-amine

Safety Information (GHS)

Pictogram(s): GHS07, GHS09. Signal word: Warning.

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
H400 (50%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
H410 (50%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

Precautionary statements: P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Request the SDS (Safety Data Sheet) for full hazard and safety documentation.

Storage & Handling

Storage: Keep the container tightly closed in a cool, dry and well-ventilated place. For detailed hazard, storage and transport information, request the SDS (Safety Data Sheet) with your inquiry.

Quotation & Packaging

Prices are confirmed by inquiry. Request a quote for current pricing, minimum order quantity (MOQ) and lead time. The pack sizes listed on this page are reference options; custom pack sizes and bulk quantities are available on request.

Quality & Compliance

Specifications and purity shown on this page are based on batch records. A Certificate of Analysis (COA) is available on request. For research and further manufacturing use only — not for direct human or therapeutic use.