[email protected]
CAS 1448030-48-5 2-fluoro-4,5-dihydrospiro[piperidine-4,7-thieno[2,3-c]pyran] hydrochloride molecular structure lightbox
CAS RN: 1448030-48-5

2-fluoro-4,5-dihydrospiro[piperidine-4,7-thieno[2,3-c]pyran] hydrochloride

Product Availability

Choose a grade to view its available package options.

1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20250413 1g / 2.5g Out of stock 30 business days Inquiry
  • Product code: starshine_CAS1448030-48-5
  • Purity/Analytical Methods: >99.0%
GET A QUOTE

1448030-48-5 / 2-fluorospiro[4,5-dihydrothieno[2,3-c]pyran-7,4'-piperidine];hydrochloride

Standard CAS: 1448030-48-5 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
1448030-48-5
Multi CAS
No
Molecular Formula
C11H15ClFNOS
Molecular Weight
263.760000
Exact Mass
263.054691
SMILES
C1COC2(CCNCC2)C3=C1C=C(S3)F.Cl
InChI
InChI=1S/C11H14FNOS.ClH/c12-9-7-8-1-6-14-11(10(8)15-9)2-4-13-5-3-11;/h7,13H,1-6H2;1H
InChIKey
NOAJGVDWZMBUHY-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
16
Aromatic heavy atom count
5
Fraction Csp3
0.64
H-bond acceptors
3
H-bond donors
1
Molar refractivity
64.96
TPSA
21.26

LogP / Solubility

WLOGP
2.46
MLOGP
2.17
XLogP3
2.46
Consensus LogP
2.36
Log S (ESOL)
-3.26
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.5
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.42
Class (SILICOS-IT)
Poorly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.58

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
Yes
Synthetic Accessibility
2.5

Customers Also Viewed

Get In Touch

Contact Us