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CAS 1448347-49-6 RG120 molecular structure lightbox
CAS RN: 1448347-49-6

RG120

Product Availability

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11 package records11 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250312 100mg In stock Shanghai Inquiry
Batchno.20250128 10mg In stock Shanghai Inquiry
Batchno.20250905 1g In stock Shanghai, Tianjin, Chengdu Inquiry
Batchno.20250623 1mg In stock Shanghai Inquiry
Batchno.20260512 250mg In stock Shanghai Inquiry
Batchno.20250303 25mg In stock Shanghai Inquiry
Batchno.20250512 50mg In stock Shanghai Inquiry
Batchno.20260217 5g In stock Shanghai Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260324 100mg In stock Inquiry
Batchno.20250811 25mg In stock Inquiry
Batchno.20250401 5mg In stock Inquiry
  • Product code: SSC-056167
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 1g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1448347-49-6
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g ≥95% 0 Out of Stock Shanghai Inquiry

1448347-49-6 / (2S)-N-[(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl]-1-(4-cyano-2-pyridinyl)-N-(5-fluoro-3-pyridinyl)-5-oxopyrrolidine-2-carboxamide

Standard CAS: 1448347-49-6 Multi CAS: No
Basic Information Computed Properties Safety & Transport

Basic Information

CAS
1448347-49-6
Multi CAS
No
Molecular Formula
C28H22ClF3N6O3
Molecular Weight
583.000000
Exact Mass
582.139401
SMILES
C1CC(=O)N([C@@H]1C(=O)N(C2=CC(=CN=C2)F)[C@@H](C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N
InChI
InChI=1S/C28H22ClF3N6O3/c29-21-4-2-1-3-20(21)25(26(40)36-18-11-28(31,32)12-18)37(19-10-17(30)14-34-15-19)27(41)22-5-6-24(39)38(22)23-9-16(13-33)7-8-35-23/h1-4,7-10,14-15,18,22,25H,5-6,11-12H2,(H,36,40)/t22-,25-/m0/s1
InChIKey
WIJZXSAJMHAVGX-DHLKQENFSA-N

Computed Properties

Structural Parameters

Heavy atom count
41
Aromatic heavy atom count
18
Fraction Csp3
0.29
Rotatable bonds
7
H-bond acceptors
6
H-bond donors
1
Molar refractivity
141.45
TPSA
119.29

LogP / Solubility

WLOGP
4.32
MLOGP
3.85
XLogP3
3.4
Consensus LogP
3.86
Log S (ESOL)
-6.04
Class (ESOL)
Insoluble
Log S (Ali)
-7.46
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.88
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.21

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
6

Safety & Transport

Pictogram(s)
Irritant Health Hazard
Signal
Danger
GHS Hazard Statements
H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral] H360 (50%): May damage fertility or the unborn child [Danger Reproductive toxicity] H360FD (25%): May damage fertility; May damage the unborn child [Danger Reproductive toxicity] H361 (25%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H372 (25%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]
Precautionary Statement Codes
P203, P260, P264, P270, P280, P301+P317, P318, P319, P330, P405, and P501

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