CAS RN: 956104-40-8
ARN-509
Product Availability
Choose a grade to view its available package options.
12 package records11 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260618 | 100g | Out of stock | Inquiry | |
| Batchno.20250421 | 100mg | In stock | Shanghai | Inquiry |
| Batchno.20250719 | 10mg | In stock | Shanghai, Tianjin | Inquiry |
| Batchno.20251126 | 1g | In stock | Shanghai, Shenzhen | Inquiry |
| Batchno.20251010 | 1mg | In stock | Shanghai, Tianjin | Inquiry |
| Batchno.20250324 | 250mg | In stock | Shanghai | Inquiry |
| Batchno.20250504 | 25g | In stock | Shanghai, Shenzhen | Inquiry |
| Batchno.20260228 | 5g | In stock | Shanghai, Tianjin | Inquiry |
| Batchno.20250324 | 5mg | In stock | Shanghai, Tianjin | Inquiry |
- Product code: starshine_CAS956104-40-8
- Purity/Analytical Methods: >99.0%
956104-40-8 / 4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide
Basic Information
CAS
956104-40-8
Multi CAS
No
Molecular Formula
C21F4H15N5O2S
Molecular Weight
477.400000
Exact Mass
477.088259
InChI
InChI=1S/C21H15F4N5O2S/c1-27-17(31)13-4-3-11(8-15(13)22)30-19(33)29(18(32)20(30)5-2-6-20)12-7-14(21(23,24)25)16(9-26)28-10-12/h3-4,7-8,10H,2,5-6H2,1H3,(H,27,31)
InChIKey
HJBWBFZLDZWPHF-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
33
Aromatic heavy atom count
12
Fraction Csp3
0.29
Rotatable bonds
3
H-bond acceptors
5
H-bond donors
1
Molar refractivity
112.89
TPSA
89.33
LogP / Solubility
WLOGP
3.53
MLOGP
3.14
XLogP3
3
Consensus LogP
3.22
Log S (ESOL)
-5.1
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.02
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-6.05
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.12
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
4
Customers Also Viewed
-
-
Methyl (1-Adamantanyl 5-acetamido-7,8,9-tri-O-acetyl-5-N,4- O-carbonyl-3,5-dideoxy-2-thio-D-glycero-a-D-galacto-non-2-ulopyranoside) onate
- CAS RN: 956107-32-7
- Product Code: SSC-211107
-
(3S)-3-aMino-1-Methyl-2-Pyrrolidinone hydrochloride
- CAS RN: 956109-55-0
- Product Code: starshine_CAS956109-55-0
- Purity/Analytical method: >99.0%
-
(S)-3-aMino-1-Methylpiperidin-2-one hydrochloride
- CAS RN: 956109-56-1
- Product Code: SSC-211108
-
(S)-3-aMino-1-Methylazepan-2-one hydrochloride
- CAS RN: 956109-57-2
- Product Code: starshine_CAS956109-57-2
- Purity/Analytical method: >99.0%
-
CRT0066101
- CAS RN: 956121-30-5
- Product Code: starshine_CAS956121-30-5
- Purity/Analytical method: >99.0%
