CAS RN: 948557-43-5
Tie2 kinase inhibitor
Product Availability
Choose a grade to view its available package options.
8 package records5 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250325 | 5mg / 25mg | Out of stock | 5-7 business days | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20251227 | 100mg | In stock | Shanghai | Inquiry | |
| Batchno.20260515 | 10mg | In stock | Shanghai, Wuhan | Inquiry | |
| Batchno.20250228 | 1mg | In stock | Shanghai, Wuhan | Inquiry | |
| Batchno.20250515 | 250mg | Out of stock | Inquiry | ||
| Batchno.20250207 | 25mg | Out of stock | Inquiry | ||
| Batchno.20260206 | 50mg | In stock | Shanghai | Inquiry | |
| Batchno.20260403 | 5mg | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS948557-43-5
- Purity/Analytical Methods: >99.0%
948557-43-5 / 4-[4-(6-methoxynaphthalen-2-yl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine
Basic Information
CAS
948557-43-5
Multi CAS
Yes
Molecular Formula
C26H21N3O2S
Molecular Weight
439.500000
Exact Mass
439.135448
InChI
InChI=1S/C26H21N3O2S/c1-31-22-8-5-19-15-21(4-3-20(19)16-22)25-24(17-11-13-27-14-12-17)28-26(29-25)18-6-9-23(10-7-18)32(2)30/h3-16H,1-2H3,(H,28,29)
InChIKey
SINQIEAULQKUPD-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
32
Aromatic heavy atom count
27
Fraction Csp3
0.08
Rotatable bonds
5
H-bond acceptors
4
H-bond donors
1
Molar refractivity
129.08
TPSA
67.87
LogP / Solubility
WLOGP
5.7
MLOGP
5.05
XLogP3
4.3
Consensus LogP
5.02
Log S (ESOL)
-6.45
Class (ESOL)
Insoluble
Log S (Ali)
-7.28
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.85
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.35
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
4
Customers Also Viewed
-
Fluticasone EP IMpurity B
- CAS RN: 948566-12-9
- Product Code: starshine_CAS948566-12-9
- Purity/Analytical method: >99.0%
-
-
-
-
4-Oxo-1,4-dihydro-quinoline-6-carboxylic acid Methyl ester
- CAS RN: 948571-56-0
- Product Code: SSC-210058
-
1,5-dimethyl-1H-pyrazol-4-amine hydrochloride
- CAS RN: 948571-57-1
- Product Code: SSC-210059
