CAS RN: 943757-71-9
(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol Trimethylsilyl Ether
Product Availability
Choose a grade to view its available package options.
8 package records8 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260527 | 200mg / 1g / 5g / 25g | Confirm by inquiry | Shanghai, Shandong | Inquiry |
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260107 | 100g | In stock | Shanghai | Inquiry |
| Batchno.20250301 | 100mg | In stock | Shanghai, Tianjin, Wuhan | Inquiry |
| Batchno.20250413 | 1g | In stock | Shanghai, Shenzhen, Tianjin, Chengdu | Inquiry |
| Batchno.20260205 | 250mg | In stock | Shanghai, Tianjin, Wuhan, Chengdu | Inquiry |
| Batchno.20250603 | 25g | In stock | Shanghai, Shenzhen, Tianjin | Inquiry |
| Batchno.20260325 | 500g | In stock | Shanghai | Inquiry |
| Batchno.20250510 | 5g | In stock | Shanghai, Shenzhen, Tianjin, Chengdu | Inquiry |
- Product code: ICTD3867
- Purity/Analytical Methods: >98.0%(GC)(T)
943757-71-9 / [diphenyl-[(2R)-pyrrolidin-2-yl]methoxy]-trimethylsilane
Basic Information
CAS
943757-71-9
Multi CAS
Yes
Molecular Formula
C20H27NOSi
Molecular Weight
325.500000
Exact Mass
325.186191
InChI
InChI=1S/C20H27NOSi/c1-23(2,3)22-20(19-15-10-16-21-19,17-11-6-4-7-12-17)18-13-8-5-9-14-18/h4-9,11-14,19,21H,10,15-16H2,1-3H3/t19-/m1/s1
InChIKey
RSUHWMSTWSSNOW-LJQANCHMSA-N
Computed Properties
Structural Parameters
Heavy atom count
23
Aromatic heavy atom count
12
Fraction Csp3
0.4
Rotatable bonds
5
H-bond acceptors
2
H-bond donors
1
Molar refractivity
99.12
TPSA
21.26
LogP / Solubility
WLOGP
4.53
MLOGP
4
XLogP3
4.53
Consensus LogP
4.35
Log S (ESOL)
-4.77
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.5
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-6.14
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-1.49
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
3
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