![CAS 918523-63-4 1H-Pyrrolo[2,3-b]pyridine-5-methanol, a,a-dimethyl-1-[tris(1-methylethyl)silyl]- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/918523-63-4.gif)
CAS RN: 918523-63-4
1H-Pyrrolo[2,3-b]pyridine-5-methanol, a,a-dimethyl-1-[tris(1-methylethyl)silyl]-
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20250412 | 100mg / 250mg | Out of stock | 8-10 business days | Inquiry |
- Product code: starshine_CAS918523-63-4
- Purity/Analytical Methods: >99.0%
918523-63-4 / 2-[1-tri(propan-2-yl)silylpyrrolo[2,3-b]pyridin-5-yl]propan-2-ol
Basic Information
CAS
918523-63-4
Multi CAS
Yes
Molecular Formula
C19H32N2OSi
Molecular Weight
332.600000
Exact Mass
332.228390
InChI
InChI=1S/C19H32N2OSi/c1-13(2)23(14(3)4,15(5)6)21-10-9-16-11-17(19(7,8)22)12-20-18(16)21/h9-15,22H,1-8H3
InChIKey
MXBIIYIIDGTFIP-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
23
Aromatic heavy atom count
9
Fraction Csp3
0.63
Rotatable bonds
5
H-bond acceptors
3
H-bond donors
1
Molar refractivity
101.42
TPSA
38.05
LogP / Solubility
WLOGP
5.29
MLOGP
4.67
XLogP3
5.29
Consensus LogP
5.08
Log S (ESOL)
-5.19
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.1
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-6.81
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-0.99
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
2.5
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