![CAS 918505-61-0 N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/918505-61-0.gif)
CAS RN: 918505-61-0
N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide
Product Availability
Choose a grade to view its available package options.
13 package records12 with current stock3 grade groups
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250509 | 100mg | In stock | Shanghai | Inquiry | |
| Batchno.20250506 | 10mg | Out of stock | 5-7 business days | Inquiry | |
| Batchno.20260311 | 10mg | In stock | Shanghai | Inquiry | |
| Batchno.20250319 | 1mg | In stock | Shanghai | Inquiry | |
| Batchno.20260116 | 250mg | In stock | Shanghai | Inquiry | |
| Batchno.20250205 | 25mg | In stock | Shanghai | Inquiry | |
| Batchno.20250406 | 50mg | In stock | Shanghai | Inquiry | |
| Batchno.20250524 | 5mg | In stock | Shanghai | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20260207 | 1ml | In stock | Inquiry |
- Product code: starshine_CAS918505-61-0
- Purity/Analytical Methods: >99.0%
918505-61-0 / N-[2,4-difluoro-3-(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)phenyl]propane-2-sulfonamide
Basic Information
CAS
918505-61-0
Multi CAS
Yes
Molecular Formula
C22F2H18N4O3S
Molecular Weight
456.500000
Exact Mass
456.106768
InChI
InChI=1S/C22H18F2N4O3S/c1-12(2)32(30,31)28-18-6-5-17(23)19(20(18)24)21(29)16-11-27-22-15(16)8-14(10-26-22)13-4-3-7-25-9-13/h3-12,28H,1-2H3,(H,26,27)
InChIKey
SUNCACOTKLUNHD-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
32
Aromatic heavy atom count
21
Fraction Csp3
0.14
Rotatable bonds
6
H-bond acceptors
5
H-bond donors
2
Molar refractivity
116.79
TPSA
104.81
LogP / Solubility
WLOGP
4.28
MLOGP
3.8
XLogP3
3.2
Consensus LogP
3.76
Log S (ESOL)
-5.46
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.4
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-6.9
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.46
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3
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