CAS RN: 915769-50-5
Dovitinib
Product Availability
Choose a grade to view its available package options.
6 package records6 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260421 | 5mg / 25mg / 50mg | Confirm by inquiry | Shanghai | Inquiry |
- Product code: starshine_CAS915769-50-5
- Purity/Analytical Methods: >99.0%
915769-50-5 / 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-4aH-quinolin-2-one;2-hydroxypropanoic acid;hydrate
Basic Information
CAS
915769-50-5
Multi CAS
Yes
Molecular Formula
C24FH29N6O5
Molecular Weight
500.500000
Exact Mass
500.218346
InChI
InChI=1S/C21H21FN6O.C3H6O3.H2O/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29;1-2(4)3(5)6;/h2-6,11H,7-10H2,1H3,(H,24,25)(H3,23,26,29);2,4H,1H3,(H,5,6);1H2
InChIKey
QDPVYZNVVQQULH-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
36
Aromatic heavy atom count
9
Fraction Csp3
0.33
Rotatable bonds
3
H-bond acceptors
7
H-bond donors
4
Molar refractivity
134.1
TPSA
179.64
LogP / Solubility
WLOGP
0.63
MLOGP
0.59
XLogP3
0.63
Consensus LogP
0.62
Log S (ESOL)
-3.33
Class (ESOL)
Poorly soluble
Log S (Ali)
-4.12
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-3.8
Class (SILICOS-IT)
Poorly soluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-5.32
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
6
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![CAS 915795-01-6 7-AMINO-7-METHYL-5-AZASPIRO[2.4]HEPTAN-4-ONE HCL molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/915795-01-6.gif)
![CAS 915797-21-6 Rhodium, tetrakis[μ-[(αS)-4,5,6,7-tetrachloro-1,3-dihydro-1,3-dioxo-α-tricyclo[3.3.1.13,7]dec-1-yl-2H-isoindole-2-acetato-κO2:κO2′]]di-, (Rh-Rh) molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/915797-21-6.gif)
