CAS RN: 914613-35-7
1H-1-Ethyl Candesartan Cilexetil
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20260610 | 5mg | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS914613-35-7
- Purity/Analytical Methods: >99.0%
914613-35-7 / 1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(1-ethyltetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
Basic Information
CAS
914613-35-7
Multi CAS
No
Molecular Formula
C35H38N6O6
Molecular Weight
638.700000
Exact Mass
638.285283
InChI
InChI=1S/C35H38N6O6/c1-4-41-32(37-38-39-41)28-15-10-9-14-27(28)25-20-18-24(19-21-25)22-40-31-29(16-11-17-30(31)36-34(40)44-5-2)33(42)45-23(3)46-35(43)47-26-12-7-6-8-13-26/h9-11,14-21,23,26H,4-8,12-13,22H2,1-3H3
InChIKey
HKUZPIFWPFYKBZ-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
47
Aromatic heavy atom count
26
Fraction Csp3
0.37
Rotatable bonds
11
H-bond acceptors
12
Molar refractivity
173.68
TPSA
132.48
LogP / Solubility
WLOGP
6.81
MLOGP
6.05
XLogP3
7.4
Consensus LogP
6.75
Log S (ESOL)
-7.78
Class (ESOL)
Insoluble
Log S (Ali)
-9.72
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-10.79
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.78
Drug-likeness / Medicinal Chemistry
Lipinski
No
Ghose
No
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.17
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
6
