CAS RN: 90101-16-9
Droxicam
Product Availability
Choose a grade to view its available package options.
3 package records3 with current stock1 grade group
- Product code: LIND890731
90101-16-9 / 5-methyl-6,6-dioxo-3-pyridin-2-yl-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4-dione
Basic Information
CAS
90101-16-9
Multi CAS
No
Molecular Formula
C16H11N3O5S
Molecular Weight
357.300000
Exact Mass
357.041942
InChI
InChI=1S/C16H11N3O5S/c1-18-13-14(10-6-2-3-7-11(10)25(18,22)23)24-16(21)19(15(13)20)12-8-4-5-9-17-12/h2-9H,1H3
InChIKey
OEHFRZLKGRKFAS-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
25
Aromatic heavy atom count
18
Fraction Csp3
0.06
Rotatable bonds
1
H-bond acceptors
7
Molar refractivity
89.39
TPSA
102.48
LogP / Solubility
WLOGP
0.99
MLOGP
0.89
XLogP3
1.2
Consensus LogP
1.03
Log S (ESOL)
-3.15
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.21
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-2.93
Class (SILICOS-IT)
Moderately soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-4.2
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3
Customers Also Viewed
-
-
-
-
-
-
1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
- CAS RN: 38396-39-3
- Product Code: LINB845552
