CAS RN: 895519-90-1
Flumatinib
Product Availability
Choose a grade to view its available package options.
6 package records6 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250226 | 100mg | In stock | Shanghai | Inquiry |
| Batchno.20250708 | 10mg | In stock | Shanghai | Inquiry |
| Batchno.20260309 | 250mg | In stock | Shanghai | Inquiry |
| Batchno.20251111 | 25mg | In stock | Shanghai | Inquiry |
| Batchno.20251006 | 50mg | In stock | Shanghai | Inquiry |
| Batchno.20250207 | 5mg | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS895519-90-1
- Purity/Analytical Methods: >99.0%
895519-90-1 / 4-[(4-methylpiperazin-1-yl)methyl]-N-[6-methyl-5-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-3-pyridinyl]-3-(trifluoromethyl)benzamide
Basic Information
CAS
895519-90-1
Multi CAS
No
Molecular Formula
C29F3H29N8O
Molecular Weight
562.600000
Exact Mass
562.241642
InChI
InChI=1S/C29H29F3N8O/c1-19-26(38-28-34-9-7-25(37-28)21-4-3-8-33-16-21)15-23(17-35-19)36-27(41)20-5-6-22(24(14-20)29(30,31)32)18-40-12-10-39(2)11-13-40/h3-9,14-17H,10-13,18H2,1-2H3,(H,36,41)(H,34,37,38)
InChIKey
BJCJYEYYYGBROF-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
41
Aromatic heavy atom count
24
Fraction Csp3
0.28
Rotatable bonds
7
H-bond acceptors
8
H-bond donors
2
Molar refractivity
149.69
TPSA
99.17
LogP / Solubility
WLOGP
5
MLOGP
4.45
XLogP3
3.4
Consensus LogP
4.28
Log S (ESOL)
-6.45
Class (ESOL)
Insoluble
Log S (Ali)
-7.79
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-8.31
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.6
Drug-likeness / Medicinal Chemistry
Lipinski
No
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.56
Leadlikeness
No
Synthetic Accessibility
5
Customers Also Viewed
-
![CAS 895519-91-2 BenzaMide, 4-[(4-Methyl-1-piperazinyl)Methyl]-N-[6-Methyl-5-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-3-pyridinyl]-3-(trifluoroMethyl)-, MonoMethanesulfonate (9CI) molecular structure](data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%200%200'%3E%3C/svg%3E)
BenzaMide, 4-[(4-Methyl-1-piperazinyl)Methyl]-N-[6-Methyl-5-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-3-pyridinyl]-3-(trifluoroMethyl)-, MonoMethanesulfonate (9CI)
- CAS RN: 895519-91-2
- Product Code: SSC-201551
-
-
Tert-Butyl6-bromo-4H-spiro[benzo[d][1,3]dioxine-2,4′-piperidine]-1′-carboxylate
- CAS RN: 895525-73-2
- Product Code: starshine_CAS895525-73-2
- Purity/Analytical method: >99.0%
-
6,8-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-ONE
- CAS RN: 895534-38-0
- Product Code: SSC-201555
-
Rhodium(1+), [(1,2,5,6-η)-1,5-cyclooctadiene][(2R,2’R,5R,5’R)-1,1′-(1,2-ethanediyl)bis[2,5-bis(1-methylethyl)phospholane-κP]]-, tetrafluoroborate(1-) (9CI)
- CAS RN: 895541-38-5
- Product Code: starshine_CAS895541-38-5
- Purity/Analytical method: >99.0%
-
Trifarotene
- CAS RN: 895542-09-3
- Product Code: starshine_CAS895542-09-3
- Purity/Analytical method: >99.0%
![CAS 895519-91-2 BenzaMide, 4-[(4-Methyl-1-piperazinyl)Methyl]-N-[6-Methyl-5-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-3-pyridinyl]-3-(trifluoroMethyl)-, MonoMethanesulfonate (9CI) molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/895519-91-2.gif)
![CAS 895525-73-2 Tert-Butyl6-bromo-4H-spiro[benzo[d][1,3]dioxine-2,4′-piperidine]-1′-carboxylate molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/895525-73-2.gif)
![CAS 895541-38-5 Rhodium(1+), [(1,2,5,6-η)-1,5-cyclooctadiene][(2R,2’R,5R,5’R)-1,1′-(1,2-ethanediyl)bis[2,5-bis(1-methylethyl)phospholane-κP]]-, tetrafluoroborate(1-) (9CI) molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/895541-38-5.gif)
