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CAS 885516-61-0 Cyclohexyl Ramipril Hydrochloride molecular structure lightbox
CAS RN: 885516-61-0

Cyclohexyl Ramipril Hydrochloride

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1 package records0 with current stock
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20250820 20mg Out of stock 15 business days Inquiry
  • Product code: starshine_CAS885516-61-0
  • Purity/Analytical Methods: >99.0%
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885516-61-0 / (2S,3aS,6aS)-1-[(2S)-2-[[(2S)-4-cyclohexyl-1-ethoxy-1-oxobutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid;hydrochloride

Standard CAS: 885516-61-0 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
885516-61-0
Multi CAS
Yes
Molecular Formula
C23H39CLN2O5
Molecular Weight
459.000000
Exact Mass
458.254750
InChI
InChI=1S/C23H38N2O5.ClH/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28;/h15-20,24H,3-14H2,1-2H3,(H,27,28);1H/t15-,17-,18-,19-,20-;/m0./s1
InChIKey
KYSZJGRJQYQTJD-IKZVEOHFSA-N

Computed Properties

Structural Parameters

Heavy atom count
31
Fraction Csp3
0.87
Rotatable bonds
9
H-bond acceptors
5
H-bond donors
2
Molar refractivity
120.09
TPSA
95.94

LogP / Solubility

WLOGP
3.53
MLOGP
3.14
XLogP3
3.53
Consensus LogP
3.4
Log S (ESOL)
-4.32
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.87
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-6.66
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.01

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
5

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