CAS RN: 88150-62-3
Phthaloyl amlodipine
Product Availability
Choose a grade to view its available package options.
5 package records5 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260318 | 100g | In stock | Shanghai, Shenzhen, Chengdu | Inquiry |
| Batchno.20260207 | 1kg | In stock | Shanghai | Inquiry |
| Batchno.20250913 | 25g | In stock | Shenzhen, Tianjin | Inquiry |
| Batchno.20250324 | 500g | In stock | Shanghai, Wuhan | Inquiry |
| Batchno.20250217 | 5g | In stock | Tianjin | Inquiry |
- Product code: LINP859173
88150-62-3 / 3-O-ethyl 5-O-methyl 4-(2-chlorophenyl)-2-[2-(1,3-dioxoisoindol-2-yl)ethoxymethyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Basic Information
CAS
88150-62-3
Multi CAS
Yes
Molecular Formula
C28H27CLN2O7
Molecular Weight
539.000000
Exact Mass
538.150679
InChI
InChI=1S/C28H27ClN2O7/c1-4-38-28(35)24-21(15-37-14-13-31-25(32)17-9-5-6-10-18(17)26(31)33)30-16(2)22(27(34)36-3)23(24)19-11-7-8-12-20(19)29/h5-12,23,30H,4,13-15H2,1-3H3
InChIKey
AHHPZGUFLGCZCF-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
38
Aromatic heavy atom count
12
Fraction Csp3
0.29
Rotatable bonds
9
H-bond acceptors
8
H-bond donors
1
Molar refractivity
138.33
TPSA
111.24
LogP / Solubility
WLOGP
3.6
MLOGP
3.21
XLogP3
4.6
Consensus LogP
3.8
Log S (ESOL)
-5.09
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.58
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.23
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.45
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
5
