CAS RN: 875258-85-8
YIL 781
Product Availability
Choose a grade to view its available package options.
8 package records7 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250828 | 1mg / 10mg / 25mg / 100mg | Out of stock | 5-7 business days | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250610 | 100mg | In stock | Shanghai | Inquiry | |
| Batchno.20250710 | 10mg | In stock | Shanghai | Inquiry | |
| Batchno.20250915 | 1mg | In stock | Shanghai | Inquiry | |
| Batchno.20250630 | 250mg | In stock | Shanghai | Inquiry | |
| Batchno.20250415 | 25mg | In stock | Shanghai | Inquiry | |
| Batchno.20250614 | 50mg | In stock | Shanghai | Inquiry | |
| Batchno.20251108 | 5mg | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS875258-85-8
- Purity/Analytical Methods: >99.0%
875258-85-8 / 6-(4-fluorophenoxy)-2-methyl-3-[[(3S)-1-propan-2-ylpiperidin-3-yl]methyl]quinazolin-4-one
Basic Information
CAS
875258-85-8
Multi CAS
Yes
Molecular Formula
C24FH28N3O2
Molecular Weight
409.500000
Exact Mass
409.216555
InChI
InChI=1S/C24H28FN3O2/c1-16(2)27-12-4-5-18(14-27)15-28-17(3)26-23-11-10-21(13-22(23)24(28)29)30-20-8-6-19(25)7-9-20/h6-11,13,16,18H,4-5,12,14-15H2,1-3H3/t18-/m0/s1
InChIKey
FRKXOBMDEXCHHD-SFHVURJKSA-N
Computed Properties
Structural Parameters
Heavy atom count
30
Aromatic heavy atom count
16
Fraction Csp3
0.42
Rotatable bonds
5
H-bond acceptors
5
Molar refractivity
116.65
TPSA
47.36
LogP / Solubility
WLOGP
4.76
MLOGP
4.21
XLogP3
4.1
Consensus LogP
4.36
Log S (ESOL)
-5.44
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.35
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-6.87
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.84
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5
