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CAS 866133-65-5 2-(4-FLUOROPHENYL)IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID molecular structure lightbox
CAS RN: 866133-65-5

2-(4-FLUOROPHENYL)IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID

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1 package records1 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250808 100mg / 250mg / 1g Confirm by inquiry Shanghai Inquiry
  • Product code: starshine_CAS866133-65-5
  • Purity/Analytical Methods: >99.0%
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866133-65-5 / 2-(4-fluorophenyl)imidazo[1,2-a]pyridine-6-carboxylic acid

Standard CAS: 866133-65-5 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
866133-65-5
Multi CAS
No
Molecular Formula
C14FH9N2O2
Molecular Weight
256.230000
Exact Mass
256.064806
InChI
InChI=1S/C14H9FN2O2/c15-11-4-1-9(2-5-11)12-8-17-7-10(14(18)19)3-6-13(17)16-12/h1-8H,(H,18,19)
InChIKey
NDWDOXBWVQISOA-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
19
Aromatic heavy atom count
15
Rotatable bonds
2
H-bond acceptors
3
H-bond donors
1
Molar refractivity
67.55
TPSA
54.6

LogP / Solubility

WLOGP
2.84
MLOGP
2.5
XLogP3
3.1
Consensus LogP
2.81
Log S (ESOL)
-3.67
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.71
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.92
Class (SILICOS-IT)
Poorly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.27

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
Yes
Synthetic Accessibility
1.5

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