![CAS 848217-00-5 8-chloro-2-methyl-4-(4-methylpiperazin-1-yl)-[1]benzofuro[3,2-d]pyrimidine molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/848217-00-5.gif)
CAS RN: 848217-00-5
8-chloro-2-methyl-4-(4-methylpiperazin-1-yl)-[1]benzofuro[3,2-d]pyrimidine
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20250906 | 5mg / 10mg | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS848217-00-5
- Purity/Analytical Methods: >99.0%
848217-00-5 / 8-chloro-2-methyl-4-(4-methylpiperazin-1-yl)-[1]benzofuro[3,2-d]pyrimidine
Basic Information
CAS
848217-00-5
Multi CAS
No
Molecular Formula
C16H17CLN4O
Molecular Weight
316.780000
Exact Mass
316.109089
InChI
InChI=1S/C16H17ClN4O/c1-10-18-14-12-9-11(17)3-4-13(12)22-15(14)16(19-10)21-7-5-20(2)6-8-21/h3-4,9H,5-8H2,1-2H3
InChIKey
GUJLUPNSRRNJKP-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
22
Aromatic heavy atom count
13
Fraction Csp3
0.38
Rotatable bonds
1
H-bond acceptors
5
Molar refractivity
88.77
TPSA
45.4
LogP / Solubility
WLOGP
3.09
MLOGP
2.73
XLogP3
3.3
Consensus LogP
3.04
Log S (ESOL)
-4.12
Class (ESOL)
Slightly soluble
Log S (Ali)
-4.39
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.4
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.46
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
Yes
Synthetic Accessibility
3
Customers Also Viewed
-
-
2-ETHOXY-3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE
- CAS RN: 848243-23-2
- Product Code: SSC-192475
-
2-ISOPROPOXY-3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE
- CAS RN: 848243-25-4
- Product Code: SSC-192476
-
2-CYCLOPROPYLMETHOXY-3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE
- CAS RN: 848243-26-5
- Product Code: SSC-192477
-
HS-243
- CAS RN: 848249-10-5
- Product Code: starshine_CAS848249-10-5
- Purity/Analytical method: >99.0%
-
Pemafibrate (racemate)
- CAS RN: 848258-31-1
- Product Code: starshine_CAS848258-31-1
- Purity/Analytical method: >99.0%
![CAS 848243-23-2 2-ETHOXY-3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/848243-23-2.gif)
![CAS 848243-25-4 2-ISOPROPOXY-3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/848243-25-4.gif)
![CAS 848243-26-5 2-CYCLOPROPYLMETHOXY-3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/848243-26-5.gif)
