CAS RN: 84746-24-7
2,2′-(1,4-Piperazinediyl)bis-pyrimidine
Product Availability
Choose a grade to view its available package options.
1 package records1 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250322 | 100mg / 250mg / 1g | Confirm by inquiry | Shanghai | Inquiry |
- Product code: starshine_CAS84746-24-7
- Purity/Analytical Methods: >99.0%
84746-24-7 / 2-(4-pyrimidin-2-ylpiperazin-1-yl)pyrimidine
Basic Information
CAS
84746-24-7
Multi CAS
No
Molecular Formula
C12H14N6
Molecular Weight
242.280000
Exact Mass
242.127994
InChI
InChI=1S/C12H14N6/c1-3-13-11(14-4-1)17-7-9-18(10-8-17)12-15-5-2-6-16-12/h1-6H,7-10H2
InChIKey
CGDIIYVMINKXRL-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
18
Aromatic heavy atom count
12
Fraction Csp3
0.33
Rotatable bonds
2
H-bond acceptors
6
Molar refractivity
68.49
TPSA
58.04
LogP / Solubility
WLOGP
0.59
MLOGP
0.53
XLogP3
0.9
Consensus LogP
0.67
Log S (ESOL)
-2.08
Class (ESOL)
Moderately soluble
Log S (Ali)
-1.98
Class (Ali)
Soluble
Log S (SILICOS-IT)
-1.97
Class (SILICOS-IT)
Soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.78
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5
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