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CAS 835621-07-3 Regorafenib (Hydrochloride) molecular structure lightbox
CAS RN: 835621-07-3

Regorafenib (Hydrochloride)

Product Availability

Choose a grade to view its available package options.

11 package records10 with current stock3 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260413 1ml In stock Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250709 100mg In stock Shanghai Inquiry
Batchno.20250704 10mg In stock Shanghai Inquiry
Batchno.20251230 1g In stock Shanghai Inquiry
Batchno.20260426 1mg In stock Shanghai Inquiry
Batchno.20260403 250mg In stock Shanghai Inquiry
Batchno.20251114 25mg In stock Shanghai Inquiry
Batchno.20251209 50mg In stock Shanghai Inquiry
Batchno.20250526 5g Out of stock Inquiry
Batchno.20250910 5mg In stock Shanghai Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260109 5mg / 10mg / 50mg / 250mg / 1g Confirm by inquiry Shanghai, Shandong Inquiry
  • Product code: SSC-191345
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 1g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 835621-07-3
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g ≥95% 0 Out of Stock Hong Kong Inquiry

835621-07-3 / 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide;hydrochloride

Standard CAS: 835621-07-3 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
835621-07-3
Multi CAS
No
Molecular Formula
C21H16CL2F4N4O3
Molecular Weight
519.300000
Exact Mass
518.053558
InChI
InChI=1S/C21H15ClF4N4O3.ClH/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26;/h2-10H,1H3,(H,27,31)(H2,29,30,32);1H
InChIKey
ACSWJKPZXNIVMY-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
34
Aromatic heavy atom count
18
Fraction Csp3
0.1
Rotatable bonds
5
H-bond acceptors
4
H-bond donors
3
Molar refractivity
120.44
TPSA
92.35

LogP / Solubility

WLOGP
6.11
MLOGP
5.42
XLogP3
6.11
Consensus LogP
5.88
Log S (ESOL)
-6.97
Class (ESOL)
Insoluble
Log S (Ali)
-8.23
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-8.71
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.55

Drug-likeness / Medicinal Chemistry

Lipinski
No
Ghose
No
Veber
Yes
Egan
No
Muegge
No
Bioavailability score
0.17
Leadlikeness
No
Synthetic Accessibility
2.5

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