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CAS 81246-81-3 5′-O-(4,4′-DiMethoxytrityl)-3′-O-t-butyldiMethylsilyl uridine molecular structure lightbox
CAS RN: 81246-81-3

5′-O-(4,4′-DiMethoxytrityl)-3′-O-t-butyldiMethylsilyl uridine

Product Availability

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1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20250107 100mg / 250mg / 1g / 5g Out of stock 15 business days Inquiry
  • Product code: SSC-189767
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 1g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 81246-81-3
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g ≥95% 0 Out of Stock Beijing Inquiry

81246-81-3 / 1-[5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]pyrimidine-2,4-dione

Standard CAS: 81246-81-3 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
81246-81-3
Multi CAS
Yes
Molecular Formula
C36H44N2O8Si
Molecular Weight
660.800000
Exact Mass
660.286693
InChI
InChI=1S/C36H44N2O8Si/c1-35(2,3)47(6,7)46-32-29(45-33(31(32)40)38-22-21-30(39)37-34(38)41)23-44-36(24-11-9-8-10-12-24,25-13-17-27(42-4)18-14-25)26-15-19-28(43-5)20-16-26/h8-22,29,31-33,40H,23H2,1-7H3,(H,37,39,41)
InChIKey
ZATGYRPVDYINRF-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
47
Aromatic heavy atom count
24
Fraction Csp3
0.39
Rotatable bonds
11
H-bond acceptors
9
H-bond donors
2
Molar refractivity
181.57
TPSA
121.24

LogP / Solubility

WLOGP
5.21
MLOGP
4.64
XLogP3
5.21
Consensus LogP
5.02
Log S (ESOL)
-6.87
Class (ESOL)
Insoluble
Log S (Ali)
-8.74
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-9.6
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.05

Drug-likeness / Medicinal Chemistry

Lipinski
No
Ghose
No
Veber
No
Egan
Yes
Muegge
No
Bioavailability score
0.56
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
7

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