CAS RN: 80259-18-3
JP1302
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20250919 | 50mg / 100mg | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS80259-18-3
- Purity/Analytical Methods: >99.0%
80259-18-3 / N-[4-(4-methylpiperazin-1-yl)phenyl]acridin-9-amine
Basic Information
CAS
80259-18-3
Multi CAS
Yes
Molecular Formula
C24H24N4
Molecular Weight
368.500000
Exact Mass
368.200097
InChI
InChI=1S/C24H24N4/c1-27-14-16-28(17-15-27)19-12-10-18(11-13-19)25-24-20-6-2-4-8-22(20)26-23-9-5-3-7-21(23)24/h2-13H,14-17H2,1H3,(H,25,26)
InChIKey
QZKGUNQLVFEEBA-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
28
Aromatic heavy atom count
20
Fraction Csp3
0.21
Rotatable bonds
3
H-bond acceptors
4
H-bond donors
1
Molar refractivity
118.68
TPSA
31.4
LogP / Solubility
WLOGP
4.88
MLOGP
4.32
XLogP3
5
Consensus LogP
4.73
Log S (ESOL)
-5.53
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.11
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-6.47
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.5
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
PAINS alerts
1
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
3.5
Customers Also Viewed
-
-
-
-
-
(isoquinolin-5-yloxy)-acetic acid
- CAS RN: 80278-25-7
- Product Code: starshine_CAS80278-25-7
- Purity/Analytical method: >99.0%
-
![CAS 80277-04-9 5-chlorobenzo[c][1,2,5]oxadiazol-4-amine molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/80277-04-9.gif)
![CAS 80278-94-0 1,2,3,3A,4,8B-HEXAHYDROCYCLOPENTA[B]INDOLE molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/80278-94-0.gif)