CAS RN: 7449-74-3

N-Methyl-N-trimethylsilylacetamide [Trimethylsilylating Agent]

Product Availability

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1 package records1 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20251210 1ml / 5ml / 25ml / 100ml / 500ml Confirm by inquiry Shanghai, Shandong, Chongqing Inquiry
  • Product code: SSC-183942
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 5g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 7449-74-3
Pack Size Recorded Purity Available Qty Ship From Inquiry
5g ≥95% 0 Out of Stock Hong Kong Inquiry

7449-74-3 / N-methyl-N-trimethylsilylacetamide

Standard CAS: 7449-74-3 Multi CAS: Yes

Basic Information

CAS
7449-74-3
Multi CAS
Yes
Molecular Formula
C6H15NOSi
Molecular Weight
145.270000
Exact Mass
145.092291
InChI
InChI=1S/C6H15NOSi/c1-6(8)7(2)9(3,4)5/h1-5H3
InChIKey
QHUOBLDKFGCVCG-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
9
Fraction Csp3
0.83
Rotatable bonds
1
H-bond acceptors
1
Molar refractivity
41.79
TPSA
20.31

LogP / Solubility

WLOGP
1.3
MLOGP
1.14
XLogP3
1.3
Consensus LogP
1.25
Log S (ESOL)
-1.49
Class (ESOL)
Soluble
Log S (Ali)
-1.69
Class (Ali)
Soluble
Log S (SILICOS-IT)
-1.8
Class (SILICOS-IT)
Soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.68

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
1.5

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