5139 °F at 760 mmHg (NIOSH, 2024)
4946 °F at 760 mmHg (NTP, 1992)
2730 °C
5139 °F
Density
8.9 (Metal) (NIOSH, 2024) - Denser than water; will sink
8.908 (NTP, 1992) - Denser than water; will sink
8.908
8.9 g/cm³
8.90 (metal)
Physical Description
Lustrous, silvery, odorless metallic solid. Insoluble in water.
Raney Nickel catalyst, is extremely fine powdered nickel. It is grayish colored. Insoluble in water. Nickel catalyst is used to promote the chemical action in manufacturing synthetics and to process vegetable oil and petroleum. If exposed to air or moisture, it may become hot enough to ignite. It is insoluble in water and does not react with larger volumes of water.
Pellets or Large Crystals; Pellets or Large Crystals, Other Solid; Dry Powder, Pellets or Large Crystals; Other Solid; Dry Powder, Other Solid; Dry Powder; Water or Solvent Wet Solid
Metal: Lustrous, silvery, odorless solid.
SILVERY METALLIC LUSTROUS SOLID IN VARIOUS FORMS.
Appearance
SILVERY METAL
Metal: Lustrous, silvery solid.
Lustrous, white, hard, ferromagnetic metal; face centered cubic crystals
Silvery, malleable, magnetic metal
State
Solid
Computed Properties
Structural Parameters
Heavy atom count
1
TPSA
0.0000
LogP / Solubility
MLOGP
-0.02
Consensus LogP
-0.01
Log S (ESOL)
-0.2
Class (ESOL)
Very soluble
Log S (Ali)
-0.04
Class (Ali)
Very soluble
Log S (SILICOS-IT)
-0.04
Class (SILICOS-IT)
Very soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.08
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1
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