CAS RN: 7440-02-0

Skeletal Nickel Catalyst slurry in Water [Active catalyst for Hydrogenation]

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  • Product code: ICTS0487
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7440-02-0 / nickel

Standard CAS: 7440-02-0 Multi CAS: Yes

Basic Information

CAS
7440-02-0
Multi CAS
Yes
Molecular Formula
IN
Molecular Weight
58.693000
Exact Mass
57.935342
InChI
InChI=1S/Ni
InChIKey
PXHVJJICTQNCMI-UHFFFAOYSA-N

Physical Properties

Melting Point
2831 °F (NIOSH, 2024) 2651 °F (NTP, 1992) 2831 °F 1455 °C
Boiling Point
5139 °F at 760 mmHg (NIOSH, 2024) 4946 °F at 760 mmHg (NTP, 1992) 2730 °C 5139 °F
Density
8.9 (Metal) (NIOSH, 2024) - Denser than water; will sink 8.908 (NTP, 1992) - Denser than water; will sink 8.908 8.9 g/cm³ 8.90 (metal)
Physical Description
Lustrous, silvery, odorless metallic solid. Insoluble in water. Raney Nickel catalyst, is extremely fine powdered nickel. It is grayish colored. Insoluble in water. Nickel catalyst is used to promote the chemical action in manufacturing synthetics and to process vegetable oil and petroleum. If exposed to air or moisture, it may become hot enough to ignite. It is insoluble in water and does not react with larger volumes of water. Pellets or Large Crystals; Pellets or Large Crystals, Other Solid; Dry Powder, Pellets or Large Crystals; Other Solid; Dry Powder, Other Solid; Dry Powder; Water or Solvent Wet Solid Metal: Lustrous, silvery, odorless solid. SILVERY METALLIC LUSTROUS SOLID IN VARIOUS FORMS.
Appearance
SILVERY METAL Metal: Lustrous, silvery solid. Lustrous, white, hard, ferromagnetic metal; face centered cubic crystals Silvery, malleable, magnetic metal
State
Solid

Computed Properties

Structural Parameters

Heavy atom count
1
TPSA
0.0000

LogP / Solubility

MLOGP
-0.02
Consensus LogP
-0.01
Log S (ESOL)
-0.2
Class (ESOL)
Very soluble
Log S (Ali)
-0.04
Class (Ali)
Very soluble
Log S (SILICOS-IT)
-0.04
Class (SILICOS-IT)
Very soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.08

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1

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