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CAS 74011-47-5 Norfloxacin Ethyl Ester molecular structure lightbox
CAS RN: 74011-47-5

Norfloxacin Ethyl Ester

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1 package records1 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250306 100mg In stock Shanghai Inquiry
  • Product code: starshine_CAS74011-47-5
  • Purity/Analytical Methods: >99.0%
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74011-47-5 / ethyl 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylate

Standard CAS: 74011-47-5 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
74011-47-5
Multi CAS
No
Molecular Formula
C18FH22N3O3
Molecular Weight
347.400000
Exact Mass
347.164520
InChI
InChI=1S/C18H22FN3O3/c1-3-21-11-13(18(24)25-4-2)17(23)12-9-14(19)16(10-15(12)21)22-7-5-20-6-8-22/h9-11,20H,3-8H2,1-2H3
InChIKey
WKZAVCCKKJQNCJ-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
25
Aromatic heavy atom count
10
Fraction Csp3
0.44
Rotatable bonds
4
H-bond acceptors
6
H-bond donors
1
Molar refractivity
94.88
TPSA
63.57

LogP / Solubility

WLOGP
1.75
MLOGP
1.55
XLogP3
1.4
Consensus LogP
1.57
Log S (ESOL)
-3.13
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.67
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.85
Class (SILICOS-IT)
Poorly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.6

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
Yes
Synthetic Accessibility
2.5

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