[email protected]
CAS 710350-66-6 8-(2,2,2-trifluoroethyl)-1,4-dioxa-8-azaspiro[4.5]decane(WXFC0424) molecular structure lightbox
CAS RN: 710350-66-6

8-(2,2,2-trifluoroethyl)-1,4-dioxa-8-azaspiro[4.5]decane(WXFC0424)

Product Availability

Choose a grade to view its available package options.

1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20260312 100mg / 250mg / 1g Out of stock 15 business days Inquiry
  • Product code: starshine_CAS710350-66-6
  • Purity/Analytical Methods: >99.0%
GET A QUOTE

710350-66-6 / 8-(2,2,2-trifluoroethyl)-1,4-dioxa-8-azaspiro[4.5]decane

Standard CAS: 710350-66-6 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
710350-66-6
Multi CAS
No
Molecular Formula
C9F3H14NO2
Molecular Weight
225.210000
Exact Mass
225.097663
InChI
InChI=1S/C9H14F3NO2/c10-9(11,12)7-13-3-1-8(2-4-13)14-5-6-15-8/h1-7H2
InChIKey
HNIHCKHQRCLHDZ-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
15
Fraction Csp3
1
Rotatable bonds
1
H-bond acceptors
3
Molar refractivity
46.36
TPSA
21.7

LogP / Solubility

WLOGP
1.39
MLOGP
1.22
XLogP3
1.3
Consensus LogP
1.3
Log S (ESOL)
-2.04
Class (ESOL)
Moderately soluble
Log S (Ali)
-2.41
Class (Ali)
Moderately soluble
Log S (SILICOS-IT)
-2.4
Class (SILICOS-IT)
Moderately soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.11

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
2.5

Customers Also Viewed

Get In Touch

Contact Us