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CAS 69304-44-5 3′,5′-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)guanosine molecular structure lightbox
CAS RN: 69304-44-5

3′,5′-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)guanosine

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1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20250417 250mg / 1g Out of stock 15 business days Inquiry
  • Product code: starshine_CAS69304-44-5
  • Purity/Analytical Methods: >99.0%
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69304-44-5 / 2-amino-9-[9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-1H-purin-6-one

Standard CAS: 69304-44-5 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
69304-44-5
Multi CAS
Yes
Molecular Formula
C22H39N5O6Si2
Molecular Weight
525.700000
Exact Mass
525.243887
InChI
InChI=1S/C22H39N5O6Si2/c1-11(2)34(12(3)4)30-9-15-18(32-35(33-34,13(5)6)14(7)8)17(28)21(31-15)27-10-24-16-19(27)25-22(23)26-20(16)29/h10-15,17-18,21,28H,9H2,1-8H3,(H3,23,25,26,29)/t15-,17-,18-,21-/m1/s1
InChIKey
CWVNMKRKFJYCCC-QTQZEZTPSA-N

Computed Properties

Structural Parameters

Heavy atom count
35
Aromatic heavy atom count
9
Fraction Csp3
0.77
Rotatable bonds
5
H-bond acceptors
10
H-bond donors
3
Molar refractivity
136.29
TPSA
146.74

LogP / Solubility

WLOGP
2.92
MLOGP
2.61
XLogP3
2.92
Consensus LogP
2.82
Log S (ESOL)
-4.8
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.98
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-6.1
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.86

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
No
Egan
No
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
5

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