![CAS 649735-46-6 1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo-[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol molecular structure](https://starshinechemical.com/wp-content/uploads/2022/03/649735-46-6.png)
CAS RN: 649735-46-6
1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo-[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol
Product Availability
Choose a grade to view its available package options.
14 package records10 with current stock4 grade groups
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20260518 | 10mg | Out of stock | 8-10 business days | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20260529 | 100mg | In stock | Shanghai | Inquiry | |
| Batchno.20250227 | 1g | Out of stock | Inquiry | ||
| Batchno.20260423 | 1mg | In stock | Shanghai | Inquiry | |
| Batchno.20250614 | 250mg | Out of stock | Inquiry | ||
| Batchno.20250220 | 25mg | Out of stock | Inquiry | ||
| Batchno.20250711 | 2mg | In stock | Shanghai | Inquiry | |
| Batchno.20250705 | 50mg | In stock | Shanghai | Inquiry | |
| Batchno.20250618 | 5mg | In stock | Shanghai | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20260225 | 1ml | In stock | Inquiry |
- Product code: SSC-174617
Historical Factory Record
Historical Supply Reference
This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
- Pack sizes on record: 0.25g
- Available purity: ≥95%
- Inventory rows with stock: 0
- Bulk packaging: confirmed by inquiry
Reference Pack Sizes
Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.
| Pack Size | Recorded Purity | Available Qty | Ship From | Inquiry |
|---|---|---|---|---|
| 0.25g | ≥95% | 0 Out of Stock | Shenzhen | Inquiry |
649735-46-6 / (2R)-1-[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-ol
Basic Information
CAS
649735-46-6
Multi CAS
Yes
Molecular Formula
C19FH19N4O3
Molecular Weight
370.400000
Exact Mass
370.144119
InChI
InChI=1S/C19H19FN4O3/c1-10-6-13-14(23-10)4-5-15(17(13)20)27-19-18-12(3)16(26-8-11(2)25)7-24(18)22-9-21-19/h4-7,9,11,23,25H,8H2,1-3H3/t11-/m1/s1
InChIKey
WCWUXEGQKLTGDX-LLVKDONJSA-N
Computed Properties
Structural Parameters
Heavy atom count
27
Aromatic heavy atom count
18
Fraction Csp3
0.26
Rotatable bonds
5
H-bond acceptors
6
H-bond donors
2
Molar refractivity
97.97
TPSA
84.67
LogP / Solubility
WLOGP
3.52
MLOGP
3.12
XLogP3
3
Consensus LogP
3.21
Log S (ESOL)
-4.52
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.14
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-5.59
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.48
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5
