CAS RN: 600157-67-3
3-AMINO-3,4-DIHYDRO-1,5-NAPHTHYRIDIN-2(1H)-ONE
- Product code: SSC-168598
Historical Factory Record
Historical Supply Reference
This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
- Pack sizes on record: 1g
- Available purity: ＞95%
- Inventory rows with stock: 0
- Bulk packaging: confirmed by inquiry
Reference Pack Sizes
Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.
| Pack Size | Recorded Purity | Available Qty | Ship From | Inquiry |
|---|---|---|---|---|
| 1g | ＞95% | 0 Out of Stock | Shenzhen | Inquiry |
600157-67-3 / 3-amino-3,4-dihydro-1H-1,5-naphthyridin-2-one
Basic Information
CAS
600157-67-3
Multi CAS
No
Molecular Formula
C8H9N3O
Molecular Weight
163.180000
Exact Mass
163.074562
InChI
InChI=1S/C8H9N3O/c9-5-4-7-6(11-8(5)12)2-1-3-10-7/h1-3,5H,4,9H2,(H,11,12)
InChIKey
WWPPXDOOKMWVDN-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
12
Aromatic heavy atom count
6
Fraction Csp3
0.25
H-bond acceptors
3
H-bond donors
2
Molar refractivity
44.55
TPSA
68.01
LogP / Solubility
WLOGP
-0.1
MLOGP
-0.09
XLogP3
-0.8
Consensus LogP
-0.33
Log S (ESOL)
-1.16
Class (ESOL)
Soluble
Log S (Ali)
-0.83
Class (Ali)
Very soluble
Log S (SILICOS-IT)
-0.64
Class (SILICOS-IT)
Very soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.78
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
2
Customers Also Viewed
-
2,7,12-tribromo-5,5′,10,10′,15,15′-hexahexyltruxene
- CAS RN: 600172-86-9
- Product Code: SSC-168606
-
4-[(2-AMino-phenylaMino)-Methyl]-piperidine-1-carboxylic acid tert-butyl ester
- CAS RN: 600725-25-5
- Product Code: SSC-168655
-
7-[2-(Cyclopropylmethoxy)-6-hydroxyphenyl]-1,4-dihydro-5-(3S)-3-piperidinyl-2H-pyrido[2,3-d][1,3]oxazin-2-one
- CAS RN: 600734-02-9
- Product Code: starshine_CAS600734-02-9
- Purity/Analytical method: >99.0%
-
7-[2-(Cyclopropylmethoxy)-6-hydroxyphenyl]-1,4-dihydro-5-[(3S)-3-piperidinyl]-2H-pyrido[2,3-d][1,3]oxazin-2-one hydrochloride
- CAS RN: 600734-06-3
- Product Code: starshine_CAS600734-06-3
- Purity/Analytical method: >99.0%
-
3-Iodo-N-[(benzyloxy)carbonyl]-O-benzyl-L-tyrosine Benzyl Ester
- CAS RN: 600737-79-9
- Product Code: SSC-168658
-
O-Benzyl-N-[(benzyloxy)carbonyl]-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-L-tyrosine Benzyl Ester
- CAS RN: 600737-82-4
- Product Code: SSC-168659
![CAS 600725-25-5 4-[(2-AMino-phenylaMino)-Methyl]-piperidine-1-carboxylic acid tert-butyl ester molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/600725-25-5.gif)
![CAS 600734-02-9 7-[2-(Cyclopropylmethoxy)-6-hydroxyphenyl]-1,4-dihydro-5-(3S)-3-piperidinyl-2H-pyrido[2,3-d][1,3]oxazin-2-one molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/600734-02-9.gif)
![CAS 600734-06-3 7-[2-(Cyclopropylmethoxy)-6-hydroxyphenyl]-1,4-dihydro-5-[(3S)-3-piperidinyl]-2H-pyrido[2,3-d][1,3]oxazin-2-one hydrochloride molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/600734-06-3.gif)
![CAS 600737-79-9 3-Iodo-N-[(benzyloxy)carbonyl]-O-benzyl-L-tyrosine Benzyl Ester molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/600737-79-9.gif)
![CAS 600737-82-4 O-Benzyl-N-[(benzyloxy)carbonyl]-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-L-tyrosine Benzyl Ester molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/CB02701787.gif)