CAS RN: 5734-73-6
(4-Chloro-6-methyl-pyrimidin-2-yl)-cyclopropyl-amine
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20251230 | 250mg / 1g | Out of stock | 8-10 business days | Inquiry |
- Product code: starshine_CAS5734-73-6
- Purity/Analytical Methods: >99.0%
5734-73-6 / 4-chloro-N-cyclopropyl-6-methylpyrimidin-2-amine
Basic Information
CAS
5734-73-6
Multi CAS
No
Molecular Formula
C8H10CLN3
Molecular Weight
183.640000
Exact Mass
183.056325
InChI
InChI=1S/C8H10ClN3/c1-5-4-7(9)12-8(10-5)11-6-2-3-6/h4,6H,2-3H2,1H3,(H,10,11,12)
InChIKey
IIULORVJUVCTKK-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
12
Aromatic heavy atom count
6
Fraction Csp3
0.5
Rotatable bonds
2
H-bond acceptors
3
H-bond donors
1
Molar refractivity
48.42
TPSA
37.81
LogP / Solubility
WLOGP
2.01
MLOGP
1.77
XLogP3
2.4
Consensus LogP
2.06
Log S (ESOL)
-2.48
Class (ESOL)
Moderately soluble
Log S (Ali)
-2.52
Class (Ali)
Moderately soluble
Log S (SILICOS-IT)
-2.76
Class (SILICOS-IT)
Moderately soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.41
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5
