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CAS 53-34-9 Fluprednisolone molecular structure lightbox
CAS RN: 53-34-9

Fluprednisolone

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1 package records0 with current stock
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20250921 5mg / 25mg Out of stock 5-7 business days Inquiry
  • Product code: starshine_CAS53-34-9
  • Purity/Analytical Methods: >99.0%
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53-34-9 / 6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

Standard CAS: 53-34-9 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
53-34-9
Multi CAS
Yes
Molecular Formula
C21FH27O5
Molecular Weight
378.400000
Exact Mass
378.184252
InChI
InChI=1S/C21H27FO5/c1-19-5-3-11(24)7-14(19)15(22)8-12-13-4-6-21(27,17(26)10-23)20(13,2)9-16(25)18(12)19/h3,5,7,12-13,15-16,18,23,25,27H,4,6,8-10H2,1-2H3/t12-,13-,15-,16-,18+,19-,20-,21-/m0/s1
InChIKey
MYYIMZRZXIQBGI-HVIRSNARSA-N

Computed Properties

Structural Parameters

Heavy atom count
27
Fraction Csp3
0.71
Rotatable bonds
2
H-bond acceptors
5
H-bond donors
3
Molar refractivity
95.33
TPSA
94.83

LogP / Solubility

WLOGP
1.51
MLOGP
1.35
XLogP3
1.4
Consensus LogP
1.42
Log S (ESOL)
-3
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.75
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.61
Class (SILICOS-IT)
Poorly soluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.96

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
7

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