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CAS 51220-73-6 N,O-Bis(trimethylsilyl)-L-tyrosine trimethylsilyl ester molecular structure lightbox
CAS RN: 51220-73-6

N,O-Bis(trimethylsilyl)-L-tyrosine trimethylsilyl ester

  • Product code: SSC-158058
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 1g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 51220-73-6
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g ≥95% 0 Out of Stock Hong Kong Inquiry

51220-73-6 / trimethylsilyl (2S)-2-(trimethylsilylamino)-3-(4-trimethylsilyloxyphenyl)propanoate

Standard CAS: 51220-73-6 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
51220-73-6
Multi CAS
No
Molecular Formula
C18H35NO3Si3
Molecular Weight
397.700000
Exact Mass
397.192474
InChI
InChI=1S/C18H35NO3Si3/c1-23(2,3)19-17(18(20)22-25(7,8)9)14-15-10-12-16(13-11-15)21-24(4,5)6/h10-13,17,19H,14H2,1-9H3/t17-/m0/s1
InChIKey
WMWBCQXPKSQMOK-KRWDZBQOSA-N

Computed Properties

Structural Parameters

Heavy atom count
25
Aromatic heavy atom count
6
Fraction Csp3
0.61
Rotatable bonds
8
H-bond acceptors
4
H-bond donors
1
Molar refractivity
113.83
TPSA
47.56

LogP / Solubility

WLOGP
4.61
MLOGP
4.08
XLogP3
4.61
Consensus LogP
4.43
Log S (ESOL)
-4.86
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.15
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.03
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.87

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
3

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