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CAS 474774-33-9 tert-butyl-dimethyl-[[(2R)-pyrrolidin-2-yl]methoxy]silane molecular structure lightbox
CAS RN: 474774-33-9

tert-butyl-dimethyl-[[(2R)-pyrrolidin-2-yl]methoxy]silane

  • Product code: SSC-154429
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 5g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 474774-33-9
Pack Size Recorded Purity Available Qty Ship From Inquiry
5g ≥95% 0 Out of Stock Beijing Inquiry

474774-33-9 / tert-butyl-dimethyl-(pyrrolidin-2-ylmethoxy)silane

Standard CAS: 474774-33-9 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
474774-33-9
Multi CAS
Yes
Molecular Formula
C11H25NOSi
Molecular Weight
215.410000
Exact Mass
215.170541
InChI
InChI=1S/C11H25NOSi/c1-11(2,3)14(4,5)13-9-10-7-6-8-12-10/h10,12H,6-9H2,1-5H3
InChIKey
SCSMCZJZQYDACU-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
14
Fraction Csp3
1
Rotatable bonds
3
H-bond acceptors
2
H-bond donors
1
Molar refractivity
64.17
TPSA
21.26

LogP / Solubility

WLOGP
2.76
MLOGP
2.43
XLogP3
2.76
Consensus LogP
2.65
Log S (ESOL)
-2.72
Class (ESOL)
Moderately soluble
Log S (Ali)
-3.32
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.71
Class (SILICOS-IT)
Poorly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.07

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
2

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