CAS RN: 445430-58-0
IKK Inhibitor III, BMS-345541
Product Availability
Choose a grade to view its available package options.
14 package records14 with current stock3 grade groups
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250328 | 1ml | In stock | Inquiry |
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260112 | 100mg | In stock | Shanghai | Inquiry |
| Batchno.20250529 | 10mg | In stock | Shanghai | Inquiry |
| Batchno.20260225 | 1g | In stock | Shanghai | Inquiry |
| Batchno.20260223 | 1mg | In stock | Shanghai | Inquiry |
| Batchno.20260413 | 250mg | In stock | Shanghai | Inquiry |
| Batchno.20250830 | 25mg | In stock | Shanghai | Inquiry |
| Batchno.20251010 | 50mg | In stock | Shanghai | Inquiry |
| Batchno.20260204 | 5mg | In stock | Shanghai | Inquiry |
- Product code: SSC-152590
Historical Factory Record
Historical Supply Reference
This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
- Pack sizes on record: 0.25g
- Available purity: ≥95%
- Inventory rows with stock: 0
- Bulk packaging: confirmed by inquiry
Reference Pack Sizes
Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.
| Pack Size | Recorded Purity | Available Qty | Ship From | Inquiry |
|---|---|---|---|---|
| 0.25g | ≥95% | 0 Out of Stock | Beijing | Inquiry |
445430-58-0 / N'-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine
Basic Information
CAS
445430-58-0
Multi CAS
Yes
Molecular Formula
C14H17N5
Molecular Weight
255.320000
Exact Mass
255.148396
InChI
InChI=1S/C14H17N5/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18)
InChIKey
PSPFQEBFYXJZEV-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
19
Aromatic heavy atom count
13
Fraction Csp3
0.29
Rotatable bonds
3
H-bond acceptors
5
H-bond donors
2
Molar refractivity
77.51
TPSA
68.24
LogP / Solubility
WLOGP
1.87
MLOGP
1.65
XLogP3
2.3
Consensus LogP
1.94
Log S (ESOL)
-2.91
Class (ESOL)
Moderately soluble
Log S (Ali)
-3
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.23
Class (SILICOS-IT)
Poorly soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.95
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
Yes
Synthetic Accessibility
1.5
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