![CAS 443642-32-8 7-[3,5-Bis-O-[(2,4-dichlorophenyl)methyl]-2-C-methyl-beta-D-ribofuranosyl]-4-chloro-7H-pyrrolo[2,3-d]pyrimidine molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/443642-32-8.gif)
CAS RN: 443642-32-8
7-[3,5-Bis-O-[(2,4-dichlorophenyl)methyl]-2-C-methyl-beta-D-ribofuranosyl]-4-chloro-7H-pyrrolo[2,3-d]pyrimidine
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20260603 | 500mg | Out of stock | 15 business days | Inquiry |
- Product code: starshine_CAS443642-32-8
- Purity/Analytical Methods: >99.0%
443642-32-8 / 2-(4-chloropyrrolo[2,3-d]pyrimidin-7-yl)-4-[(2,4-dichlorophenyl)methoxy]-5-[(2,4-dichlorophenyl)methoxymethyl]-3-methyloxolan-3-ol
Basic Information
CAS
443642-32-8
Multi CAS
No
Molecular Formula
C26H22CL5N3O4
Molecular Weight
617.700000
Exact Mass
617.002345
InChI
InChI=1S/C26H22Cl5N3O4/c1-26(35)22(37-11-15-3-5-17(28)9-20(15)30)21(12-36-10-14-2-4-16(27)8-19(14)29)38-25(26)34-7-6-18-23(31)32-13-33-24(18)34/h2-9,13,21-22,25,35H,10-12H2,1H3
InChIKey
DCXHACRQHZYBJB-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
38
Aromatic heavy atom count
21
Fraction Csp3
0.31
Rotatable bonds
8
H-bond acceptors
7
H-bond donors
1
Molar refractivity
148.23
TPSA
78.63
LogP / Solubility
WLOGP
7.15
MLOGP
6.34
XLogP3
6.2
Consensus LogP
6.56
Log S (ESOL)
-8.05
Class (ESOL)
Insoluble
Log S (Ali)
-9.79
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-10.57
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.41
Drug-likeness / Medicinal Chemistry
Lipinski
No
Ghose
No
Veber
Yes
Egan
No
Muegge
No
Bioavailability score
0.17
Leadlikeness
No
Synthetic Accessibility
7
Customers Also Viewed
-
![CAS 443642-33-9 4-Chloro-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-Pyrrolo[2,3-d]pyrimidine molecular structure](data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%200%200'%3E%3C/svg%3E)
4-Chloro-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-Pyrrolo[2,3-d]pyrimidine
- CAS RN: 443642-33-9
- Product Code: starshine_CAS443642-33-9
- Purity/Analytical method: >99.0%
-
7-[3,5-Bis-O-[(2,4-dichlorophenyl)methyl]-2-C-methyl-beta-D-ribofuranosyl]-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine
- CAS RN: 443642-39-5
- Product Code: starshine_CAS443642-39-5
- Purity/Analytical method: >99.0%
-
4-Chloro-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
- CAS RN: 443642-40-8
- Product Code: starshine_CAS443642-40-8
- Purity/Analytical method: >99.0%
-
4-Amino-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid
- CAS RN: 443642-56-6
- Product Code: starshine_CAS443642-56-6
- Purity/Analytical method: >99.0%
-
-
(3R,4R)-rel-3,4-Piperidinediol Hydrochloride
- CAS RN: 443648-97-3
- Product Code: SSC-152346
![CAS 443642-33-9 4-Chloro-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-Pyrrolo[2,3-d]pyrimidine molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/443642-33-9.gif)
![CAS 443642-39-5 7-[3,5-Bis-O-[(2,4-dichlorophenyl)methyl]-2-C-methyl-beta-D-ribofuranosyl]-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/443642-39-5.gif)
![CAS 443642-40-8 4-Chloro-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/443642-40-8.gif)
![CAS 443642-56-6 4-Amino-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/443642-56-6.gif)
