CAS RN: 379270-37-8

Tenofovir Alafenamide

Product Availability

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14 package records14 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20251117 1g In stock Inquiry
Batchno.20260424 250mg In stock Inquiry
Batchno.20251126 50mg In stock Inquiry
Batchno.20260416 5g In stock Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260418 100mg In stock Shanghai, Shenzhen, Tianjin Inquiry
Batchno.20250104 10g In stock Shanghai Inquiry
Batchno.20251231 10mg In stock Shanghai, Wuhan Inquiry
Batchno.20250718 1g In stock Shanghai, Tianjin Inquiry
Batchno.20260528 1mg In stock Shanghai Inquiry
Batchno.20250213 250mg In stock Shanghai, Wuhan, Chengdu Inquiry
Batchno.20260509 50mg In stock Shanghai Inquiry
Batchno.20260609 50mg / 250mg / 1g / 5g / 25g Confirm by inquiry Shanghai, Shandong Inquiry
Batchno.20251107 5g In stock Shanghai, Chengdu Inquiry
Batchno.20260301 5mg In stock Shanghai, Wuhan Inquiry
  • Product code: SSC-145384
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 1g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 379270-37-8
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g ≥95% 0 Out of Stock Shenzhen Inquiry

379270-37-8 / propan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate

Standard CAS: 379270-37-8 Multi CAS: Yes

Basic Information

CAS
379270-37-8
Multi CAS
Yes
Molecular Formula
C21H29N6O5P
Molecular Weight
476.500000
Exact Mass
476.193705
InChI
InChI=1S/C21H29N6O5P/c1-14(2)31-21(28)16(4)26-33(29,32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27/h5-9,11-12,14-16H,10,13H2,1-4H3,(H,26,29)(H2,22,23,24)/t15-,16+,33+/m1/s1
InChIKey
LDEKQSIMHVQZJK-CAQYMETFSA-N

Computed Properties

Structural Parameters

Heavy atom count
33
Aromatic heavy atom count
15
Fraction Csp3
0.43
Rotatable bonds
11
H-bond acceptors
10
H-bond donors
2
Molar refractivity
123.65
TPSA
143.48

LogP / Solubility

WLOGP
2.97
MLOGP
2.65
XLogP3
1.9
Consensus LogP
2.51
Log S (ESOL)
-4.28
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.61
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-6.54
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.52

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
No
Egan
No
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
4

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