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CAS 374703-78-3 PKG drug G1 molecular structure lightbox
CAS RN: 374703-78-3

PKG drug G1

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4 package records1 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20251204 10mg Out of stock Inquiry
Batchno.20260222 25mg Out of stock Inquiry
Batchno.20251007 5mg Out of stock Inquiry
Batchno.20250523 5mg / 10mg / 25mg / 100mg Confirm by inquiry Shanghai 5-7 business days Inquiry
  • Product code: starshine_CAS374703-78-3
  • Purity/Analytical Methods: >99.0%
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374703-78-3 / 4-hydroxy-5-[(2-methylindol-3-ylidene)methyl]-1,3-dihydroimidazole-2-thione

Standard CAS: 374703-78-3 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
374703-78-3
Multi CAS
Yes
Molecular Formula
C13H11N3OS
Molecular Weight
257.310000
Exact Mass
257.062283
InChI
InChI=1S/C13H11N3OS/c1-7-9(6-11-12(17)16-13(18)15-11)8-4-2-3-5-10(8)14-7/h2-6,17H,1H3,(H2,15,16,18)/b9-6+
InChIKey
BPJCCABLAZZIEJ-RMKNXTFCSA-N

Computed Properties

Structural Parameters

Heavy atom count
18
Aromatic heavy atom count
11
Fraction Csp3
0.08
Rotatable bonds
1
H-bond acceptors
3
H-bond donors
3
Molar refractivity
74.72
TPSA
64.17

LogP / Solubility

WLOGP
3.42
MLOGP
3.02
XLogP3
1.2
Consensus LogP
2.55
Log S (ESOL)
-3.98
Class (ESOL)
Poorly soluble
Log S (Ali)
-4.14
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.29
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-1.86

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
Yes
Synthetic Accessibility
1.5

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