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CAS 371244-11-0 4(3H)-Quinazolinone, 2-(chloroMethyl)-5-Methyl-3-(2-Methylphenyl)- molecular structure lightbox
CAS RN: 371244-11-0

4(3H)-Quinazolinone, 2-(chloroMethyl)-5-Methyl-3-(2-Methylphenyl)-

Product Availability

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1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20250712 250mg Out of stock 15 business days Inquiry
  • Product code: starshine_CAS371244-11-0
  • Purity/Analytical Methods: >99.0%
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371244-11-0 / 2-(chloromethyl)-5-methyl-3-(2-methylphenyl)quinazolin-4-one

Standard CAS: 371244-11-0 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
371244-11-0
Multi CAS
No
Molecular Formula
C17H15CLN2O
Molecular Weight
298.800000
Exact Mass
298.087291
InChI
InChI=1S/C17H15ClN2O/c1-11-6-3-4-9-14(11)20-15(10-18)19-13-8-5-7-12(2)16(13)17(20)21/h3-9H,10H2,1-2H3
InChIKey
ZOTCSPSVHIKHBZ-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
21
Aromatic heavy atom count
16
Fraction Csp3
0.18
Rotatable bonds
2
H-bond acceptors
3
Molar refractivity
86.37
TPSA
34.89

LogP / Solubility

WLOGP
3.74
MLOGP
3.3
XLogP3
3.5
Consensus LogP
3.51
Log S (ESOL)
-4.48
Class (ESOL)
Slightly soluble
Log S (Ali)
-4.71
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.95
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-1.89

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
2.5

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