[email protected]
CAS 357399-43-0 BUPROPION MORPHOLINOL molecular structure lightbox
CAS RN: 357399-43-0

BUPROPION MORPHOLINOL

Product Availability

Choose a grade to view its available package options.

2 package records1 with current stock1 grade group
Batch No.PackageAvailabilityInquiry
Batchno.20251119 10mg Out of stock Inquiry
Batchno.20250227 50mg In stock Inquiry
  • Product code: starshine_CAS357399-43-0
  • Purity/Analytical Methods: >99.0%
GET A QUOTE

357399-43-0 / 1-(3-chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino]propan-1-one

Standard CAS: 357399-43-0 Multi CAS: Yes
Basic Information Physical Properties Computed Properties

Basic Information

CAS
357399-43-0
Multi CAS
Yes
Molecular Formula
C13H18CLNO2
Molecular Weight
255.740000
Exact Mass
255.102607
InChI
InChI=1S/C13H18ClNO2/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10/h4-7,9,15-16H,8H2,1-3H3
InChIKey
RCOBKSKAZMVBHT-UHFFFAOYSA-N

Physical Properties

Physical Description
Solid
State
Solid

Computed Properties

Structural Parameters

Heavy atom count
17
Aromatic heavy atom count
6
Fraction Csp3
0.46
Rotatable bonds
5
H-bond acceptors
3
H-bond donors
2
Molar refractivity
69.55
TPSA
49.33

LogP / Solubility

WLOGP
2.27
MLOGP
2.01
XLogP3
2.2
Consensus LogP
2.16
Log S (ESOL)
-2.79
Class (ESOL)
Moderately soluble
Log S (Ali)
-3.3
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.81
Class (SILICOS-IT)
Poorly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.67

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
Yes
Synthetic Accessibility
2

Customers Also Viewed

Get In Touch

Contact Us