[email protected]
CAS 350042-00-1 2,5-Bis(2,2′-bipyridin-6-yl)-1,1-dimethyl-3,4-diphenylsilole molecular structure lightbox
CAS RN: 350042-00-1

2,5-Bis(2,2′-bipyridin-6-yl)-1,1-dimethyl-3,4-diphenylsilole

Product Availability

Choose a grade to view its available package options.

1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityInquiry
Batchno.20250428 1g Out of stock Inquiry
  • Product code: ICTB4233
  • Purity/Analytical Methods: >98.0%(HPLC)(N)
GET A QUOTE

350042-00-1 / 2-[1,1-dimethyl-3,4-diphenyl-5-(6-pyridin-2-yl-2-pyridinyl)silol-2-yl]-6-pyridin-2-ylpyridine

Standard CAS: 350042-00-1 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
350042-00-1
Multi CAS
No
Molecular Formula
C38H30N4Si
Molecular Weight
570.800000
Exact Mass
570.223974
InChI
InChI=1S/C38H30N4Si/c1-43(2)37(33-23-13-21-31(41-33)29-19-9-11-25-39-29)35(27-15-5-3-6-16-27)36(28-17-7-4-8-18-28)38(43)34-24-14-22-32(42-34)30-20-10-12-26-40-30/h3-26H,1-2H3
InChIKey
PEISKVGQULXWNZ-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
43
Aromatic heavy atom count
36
Fraction Csp3
0.05
Rotatable bonds
6
H-bond acceptors
4
Molar refractivity
178.93
TPSA
51.56

LogP / Solubility

WLOGP
8.92
MLOGP
7.9
XLogP3
8.92
Consensus LogP
8.58
Log S (ESOL)
-9.22
Class (ESOL)
Insoluble
Log S (Ali)
-10.68
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-11.5
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
0.13

Drug-likeness / Medicinal Chemistry

Lipinski
No
Ghose
No
Veber
Yes
Egan
No
Muegge
No
Bioavailability score
0.17
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
6

Customers Also Viewed

Get In Touch

Contact Us