[email protected]
CAS 289700-48-7 N-[4-(4-morpholinylsulfonyl)phenyl]-2,2-diphenylacetamide molecular structure lightbox
CAS RN: 289700-48-7

N-[4-(4-morpholinylsulfonyl)phenyl]-2,2-diphenylacetamide

Product Availability

Choose a grade to view its available package options.

1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20260701 5mg / 25mg Out of stock 5-7 business days Inquiry
  • Product code: starshine_CAS289700-48-7
  • Purity/Analytical Methods: >99.0%
GET A QUOTE

289700-48-7 / N-(4-morpholin-4-ylsulfonylphenyl)-2,2-diphenylacetamide

Standard CAS: 289700-48-7 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
289700-48-7
Multi CAS
No
Molecular Formula
C24H24N2O4S
Molecular Weight
436.500000
Exact Mass
436.145678
InChI
InChI=1S/C24H24N2O4S/c27-24(23(19-7-3-1-4-8-19)20-9-5-2-6-10-20)25-21-11-13-22(14-12-21)31(28,29)26-15-17-30-18-16-26/h1-14,23H,15-18H2,(H,25,27)
InChIKey
RDSZKRMMVIQMCH-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
31
Aromatic heavy atom count
18
Fraction Csp3
0.21
Rotatable bonds
6
H-bond acceptors
4
H-bond donors
1
Molar refractivity
119.38
TPSA
75.71

LogP / Solubility

WLOGP
3.48
MLOGP
3.09
XLogP3
3.2
Consensus LogP
3.26
Log S (ESOL)
-4.77
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.65
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-6.1
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.91

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3

Customers Also Viewed

Get In Touch

Contact Us