[email protected]
CAS 2288708-54-1 2-(6-bromo-8-fluoro-3-quinolyl)ethoxy-tert-butyl-dimethyl-silane molecular structure lightbox
CAS RN: 2288708-54-1

2-(6-bromo-8-fluoro-3-quinolyl)ethoxy-tert-butyl-dimethyl-silane

Product Availability

Choose a grade to view its available package options.

1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20251012 100mg / 500mg Out of stock 15 business days Inquiry
  • Product code: SSC-111391
GET A QUOTE
Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.25g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
Request Bulk Quote

Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 2288708-54-1
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.25g ≥95% 0 Out of Stock Shenzhen Inquiry

2288708-54-1 / 2-(6-bromo-8-fluoroquinolin-3-yl)ethoxy-tert-butyl-dimethylsilane

Standard CAS: 2288708-54-1 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
2288708-54-1
Multi CAS
No
Molecular Formula
C17H23BrFNOSi
Molecular Weight
384.400000
Exact Mass
383.071630
SMILES
CC(C)(C)[Si](C)(C)OCCC1=CC2=CC(=CC(=C2N=C1)F)Br
InChI
InChI=1S/C17H23BrFNOSi/c1-17(2,3)22(4,5)21-7-6-12-8-13-9-14(18)10-15(19)16(13)20-11-12/h8-11H,6-7H2,1-5H3
InChIKey
JDGDMCXPSMWHGO-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
22
Aromatic heavy atom count
10
Fraction Csp3
0.47
Rotatable bonds
4
H-bond acceptors
2
Molar refractivity
96.25
TPSA
22.12

LogP / Solubility

WLOGP
5.7
MLOGP
5.04
XLogP3
5.7
Consensus LogP
5.48
Log S (ESOL)
-5.89
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.83
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.37
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.02

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
2.5

Customers Also Viewed

Get In Touch

Contact Us