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CAS 22737-33-3 N-Methyl-N,O-bis(trimethylsilyl)hydroxylamine molecular structure lightbox
CAS RN: 22737-33-3

N-Methyl-N,O-bis(trimethylsilyl)hydroxylamine

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1 package records1 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250101 1ml In stock Shandong Inquiry
  • Product code: ICTM1077
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22737-33-3 / N-trimethylsilyl-N-trimethylsilyloxymethanamine

Standard CAS: 22737-33-3 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
22737-33-3
Multi CAS
No
Molecular Formula
C7H21NOSi2
Molecular Weight
191.420000
Exact Mass
191.116167
SMILES
CN(O[Si](C)(C)C)[Si](C)(C)C
InChI
InChI=1S/C7H21NOSi2/c1-8(10(2,3)4)9-11(5,6)7/h1-7H3
InChIKey
LXNSJZVQLMUDMT-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
11
Fraction Csp3
1
Rotatable bonds
3
H-bond acceptors
2
Molar refractivity
55.54
TPSA
12.47

LogP / Solubility

WLOGP
2.52
MLOGP
2.22
XLogP3
2.52
Consensus LogP
2.42
Log S (ESOL)
-2.42
Class (ESOL)
Moderately soluble
Log S (Ali)
-2.95
Class (Ali)
Moderately soluble
Log S (SILICOS-IT)
-3.36
Class (SILICOS-IT)
Poorly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.1

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
1.5

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