![CAS 22049-24-7 6,9-Diazaspiro[4.5]decane-7,10-dione,9-methyl- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/22049-24-7.gif)
CAS RN: 22049-24-7
6,9-Diazaspiro[4.5]decane-7,10-dione,9-methyl-
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20250426 | 1g / 2.5g | Out of stock | 30 business days | Inquiry |
- Product code: starshine_CAS22049-24-7
- Purity/Analytical Methods: >99.0%
22049-24-7 / 9-methyl-6,9-diazaspiro[4.5]decane-7,10-dione
Basic Information
CAS
22049-24-7
Multi CAS
No
Molecular Formula
C9H14N2O2
Molecular Weight
182.220000
Exact Mass
182.105528
SMILES
CN1CC(=O)NC2(C1=O)CCCC2
InChI
InChI=1S/C9H14N2O2/c1-11-6-7(12)10-9(8(11)13)4-2-3-5-9/h2-6H2,1H3,(H,10,12)
InChIKey
ZHEIXGWEQIILBB-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
13
Fraction Csp3
0.78
H-bond acceptors
2
H-bond donors
1
Molar refractivity
46.98
TPSA
49.41
LogP / Solubility
WLOGP
-0.11
MLOGP
-0.1
XLogP3
-0.1
Consensus LogP
-0.1
Log S (ESOL)
-0.9
Class (ESOL)
Very soluble
Log S (Ali)
-0.97
Class (Ali)
Very soluble
Log S (SILICOS-IT)
-0.75
Class (SILICOS-IT)
Very soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.91
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
2.5
