CAS RN: 203911-27-7
1-(5-Isoquinolinylsulfonyl)homopiperazine dihydrochloride, Fasudil dihydrochloride
Product Availability
Choose a grade to view its available package options.
4 package records3 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250612 | 100mg | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS203911-27-7
- Purity/Analytical Methods: >99.0%
203911-27-7 / 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline;dihydrochloride
Basic Information
CAS
203911-27-7
Multi CAS
No
Molecular Formula
C14H19Cl2N3O2S
Molecular Weight
364.300000
Exact Mass
363.057503
SMILES
C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl
InChI
InChI=1S/C14H17N3O2S.2ClH/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14;;/h1,3-5,7,11,15H,2,6,8-10H2;2*1H
InChIKey
NOXXIYDYFSNHDF-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
22
Aromatic heavy atom count
10
Fraction Csp3
0.36
Rotatable bonds
2
H-bond acceptors
4
H-bond donors
1
Molar refractivity
92.48
TPSA
62.3
LogP / Solubility
WLOGP
2.06
MLOGP
1.83
XLogP3
2.06
Consensus LogP
1.98
Log S (ESOL)
-3.6
Class (ESOL)
Poorly soluble
Log S (Ali)
-4.04
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-3.98
Class (SILICOS-IT)
Poorly soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.48
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
2.5
Customers Also Viewed
-
MMP INHIBITOR II
- CAS RN: 203915-59-7
- Product Code: starshine_CAS203915-59-7
- Purity/Analytical method: >99.0%
-
Thieno[2,3-c]pyridine-2-carboxaldehyde (9CI)
- CAS RN: 203922-18-3
- Product Code: SSC-095977
-
2-ETHYLHEXYL ISOCYANATE 98
- CAS RN: 20392-34-1
- Product Code: starshine_CAS20392-34-1
- Purity/Analytical method: >99.0%
-
Karenitecin
- CAS RN: 203923-89-1
- Product Code: starshine_CAS203923-89-1
- Purity/Analytical method: >99.0%
-
-
2,8-Diaza-spiro[4.5]decane-3,8-dicarboxylic acid 8-tert-butyl ester 3-ethyl ester
- CAS RN: 203934-60-5
- Product Code: SSC-095980
![CAS 203922-18-3 Thieno[2,3-c]pyridine-2-carboxaldehyde (9CI) molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/203922-18-3.gif)
![CAS 203934-60-5 2,8-Diaza-spiro[4.5]decane-3,8-dicarboxylic acid 8-tert-butyl ester 3-ethyl ester molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/203934-60-5.gif)